Hours after Knox was cleared of Meredith Kercher's murder the media frenzy that surrounded the trial and focused on the American student shows no sign of dying down.
Enigmatic and described as an innocent and hardworking young women or as a 'she-evil' sex crazed woman, Amanda Knox risks finding it hard to go back to her 'old life' as news agencies and magazine are set to battle over her interviews.
Donald Trump, the property and media tycoon who has lobbied in favour of Knox and claimed her innocence, has already said she could "become a big star" if she chose to on her return.
'For her to have spent four years in a terrible jail is just outrageous. I don't think they (the Knox family) can leave quick enough. She went to Italy to learn the language. Well, she learned the language,' he said
Meanwhile, talking about media attention, Harold Vogel, author of Entertainment Industry Economics has said Knox is an even bigger 'get' now, 'especially since she was acquitted there's not the feeling that you're contributing to someone who's committed a crime.'
Knox has already been the focus of a TV movie and several books, and Tuesday, Lifetime announced that Amanda Knox: Murder on Trial, the movie that prompted Knox to file a civil suit to prevent further distribution, will have a new epilogue when it re-airs Wednesday in the U.S.
There have also been rumours that Knox wrote her memoirs while in prison, so many point out she could easily sign a six-figure book deal.
Others however assure Knox just want to regain her privacy, as did her friend Jessica Nichols who told the press Amanda had mentioned doing translating work, or pursuing a profession more directly related to her nightmare study abroad trip.
"She wants to work with people who are wrongfully imprisoned, and hopefully use her experience to benefit others, and make something good out of all of this ugliness," Nichols said.
One thing was certain this morning however that Knox was in a hurry to leave Italy and has departed Rome's Leonardo da Vinci airport, and will land in London where she will catch a connecting flight to the United States.
Trying to avoid the press circus, the 24-year-old arrived at the airport in a Mercedes with darkened windows and waited for boarding inside a private waiting area as she attempted to stay out of public view.
Meanwhile back in Perugia, the family of slain British student Meredith Kercher remained shocked by the verdict and confirmed they are still searching for answers.
"It was a bit of a shock," said Stephanie Kercher, the victim's sister. "It's very upsetting ... We still have no answers."
Lyle Kercher, Meredith's brother said the family is still trying to understand how a decision that "was so certain two years ago has been so dramatically overturned."
"While we accept the decision that was handed down yesterday and respect the court and the Italian justice system, we do find that we are now left obviously looking at this again and thinking how a decision that was so certain two years ago has been so emphatically over turned now," he said at a news conference in Perugia.
Mr Kercher also said the last night's verdict also raised further questions.
"There is, of course, a third defendant - Rudy Guede - who is convicted, has been appealed and has been upheld and, at the time, I understand the court agreed that he was not acting alone," he said.
"Of course, if the two who were released yesterday were not the guilty parties, we are now obviously left wondering who is the other person or people, and really, for us, it feels very much almost like back to square one and the search goes on really to find out what truly happened, " he added.