Jonathan Trott has been ruled out of England's final one-day international against South Africa at Trent Bridge after suffering an injury to his hand in the match at Lord's.
The Warwickshire batsman was hit on the right hand by a delivery from Dale Steyn in the fourth ODI and has been forced to sit out the final game of the series.
England coach Andy Flower will also miss today's game after it was revealed that he has been given some time off to take a short break with him family before the Twenty20 matches against South Africa.
Flower will also be at the helm for the upcoming Twenty20 World Cup in Sri Lanka later this month as England look to defend their crown.
Fielding coach Richard Halsall will take the responsibility of coaching duties for the day-night match at Trent Bridge as England look to secure their 14th victory in 15 ODI games this year.
England will be without their second highest run scorer of the series in Trott, behind only ian Bell, with 142 runs at an average of 47.33.
Jos Butler has been added to the squad but it is likely that Jonathan Bairstow will take Trott's place in the starting XI after impressing in the final Test of the recent series against South Africa.
Bairstow's inclusion could mean that either Craig Kieswetter or Ravi Bopara move up to bat at number three as England look to round off the series with another victory.
Alastair Cook's side are already guaranteed to finish the year top of the International Cricket Council one-day rankings after securing victory at Lord's on Sunday.
"It has been an outstanding year for the team," said Kieswetter. "The side's been more about people stepping up and helping the team win as a unit. We don't feel as if we play as individuals. We play as a team and enjoy it."