Jack Wilshere
Wilshere may face a lengthy spell on the sidelines with knee ligament damageGetty

Jack Wilshere is facing yet another lengthy spell on the sidelines after scans revealed that the midfielder may have possible ankle ligament damage after being forced to come off in Arsenal's Premier League game against Manchester United at the Emirates.

The Daily Mirror reports that the midfielder will definitely be out for their midweek clash against Borussia Dortmund. Wojciech Szcesny is also doubtful for their much anticipated clash against the Germans after his unfortunate collision with Kieran Gibbs in the game against United.

The coming together left the keeper in no man's land, which eventually led to the goal after Gibbs dragged a wild effort into the net.

It will be a huge blow for Arsenal, who are already without David Ospina and will have to play Damien Martinez in goal. Their defence is already in sixes and sevens after injuries to Mathieu Debuchy and Laurent Koscielny.

Meanwhile, Wilshere's injury will be a major problem for Arsene Wenger, who was banking on the midfielder to drive their attack forward, especially with Aaron Ramsey struggling for form.

The 22-year-old received a lot of praise this season for his performance for England, where he was deployed in a deep anchor role, a position which the player admitted to finding conducive for his style of football.

Theo Walcottt is still out after picking up a minor injury in training while Mesut Ozil will not be available before January.

The Gunners need to win their game against Dortmund if they have to keep their hopes alive of topping the group, having dropped two important points against Anderlecht after leading them by three goals at the Emirates.

The title dream is all but over for the Gunners in the Premium League, as they are currently 15 points behind leaders Chelsea. They need to turn their attention to qualifying for the Champions League, something which they have accomplished for 18 years on the trot.

The results in the past few days have angered Arsenal fans from across the globe, who are accusing Wenger of mismanagement and has urged the Frenchman to reconsider his situation at the club.