Calvin Harris has pulled out of the MTV European Music Awards after being "taken ill".
The DJ will be unable to perform at the music event taking place at Glasgow's SSE Hydro on Sunday night (9 November) following concerns regarding a "heart problem."
Harris wrote on Twitter: "No EMAs for me this weekend. Got some heart problems. Heading home to see if it can be fixed x."
A message on the MTV EMA Facebook page also confirmed the reports saying: "We have some really sad news. Calvin Harris has taken ill and will not be able to perform at tomorrow's show. He sends his sincere apologies. Get well soon, Calvin!"
No further details were released about the nature of his illness.
Harris, who hails from Dumfries, Scotland, was this year, named the highest paid DJ in the world.
The 30 year-old star, who previously dated Rita Ora, first burst onto the music seen in 2007 with dance tracks such as Acceptable in the 80s and The Girls. In 2013, he became the first artist to have nine UK top 10 hits from one album.
He is currently developing an HBO comedy series about electronic music, with Trainspotting author Irvine Welsh.
U2, Alicia Keys, Ed Sheeran, Enrique Iglesias, Kiesza and Royal Blood are due to perform at the MTV awards, which will be hosted by US rapper Nicki Minaj.
The event will have a time travel theme.
With nominations in seven categories Roar singer Katy Perry leads the nominations with Ariana Grande close behind with six. Pharrell Williams is up for five trophies, including best song and best video for his global hit Happy.
Slash and actor David Hasselhoff are among the presenters at the event , while Black Sabbath's Ozzy Osbourne will be receive the EMA's Global Icon Award.
The awards are being held in Glasgow for the first time in their 20-year history.