England face South Africa in the second QBE international series match of the autumn at Twickenham.
Where to Watch
Kick-off is at 2:30pm and is live on Sky Sports 2HD on Saturday 15 November.
Live commentary is available on BBC Radio Five Live. Highlights are on BBC Three at 7:30pm and repeated on Sunday, 16 November on BBC Two at 1:30pm
England look to tick a vital box ahead of next year's World Cup by claiming a first win over South Africa under Stuart Lancaster's reign in charge.
Eleven meetings have past since England last inflicted defeat on the Springboks, with the 2012 loss at Twickenham fresh in the memory after captain Chris Robshaw's decision not to kick for the corner in the final minutes in their single-point reverse at Twickenham.
Robshaw's decision making has improve significantly since that daybut following last weekend's limp loss to world champions New Zealand, England are under pressure to provide evidence they are genuine World Cup contenders on home turf next year.
South Africa are the last team to have beaten the All Blacks but last weekend were shocked by Ireland and coach Heyneke Meyer has reacted by making five changes, with JP Pietersen and flanker Schalk Burger bolstering a formidable starting XV.
England have handed a first start to wing Anthony Watson is place of Semesa Rokoduguni in their only change from last weekend, with Marland Yarde returning to the matchday 23.
England: 15. Mike Brown; 14. Anthony Watson, 13. Brad Barritt, 12. Kyle Eastmond, 11. Jonny May; 10. Owen Farrell, 9. Danny Care; 1. Joe Marler, 2. Dylan Hartley, 3. Dave Wilson, 4. Dave Attwood, 5. Courtney Lawes, 6. Tom Wood, 7. Chris Robshaw (captain), 8. Billy Vunipola.
Replacements: 16. Robert Webber, 17. Matt Mullan, 18. Kieran Brookes, 19. George Kruis, 20. Ben Morgan, 21. Ben Youngs, 22. George Ford, 23. Marland Yarde.
South Africa: 15. Willie le Roux; 14. JP Pietersen, 13. Jan Serfontein, 12. Jean de Villiers (captain), 11. Bryan Habana; 10. Pat Lambie, 9. Cobus Reinach; 1. Tendai Mtawarira, 2. Adriaan Strauss, 3. Jannie du Plessis, 4. Eben Etzebeth, 5. Victor Matfield, 6. Marcell Coetzee, 7. Schalk Burger, 8. Duane Vermeulen.
Replacements: 16. Bismark du Plessis, 17. Trevor Nyakane, 18. Coenie Oosthuizen, 19. Bakkies Botha, 20.Teboho Mohoje, 21. Francois Hougaard, 22. Handre Pollard, 23. Cornal Hendricks.
What the coaches say
Stuart Lancaster: "It gives the team an opportunity to improve going into what's going to be a huge challenge against a very experienced, and hugely motivated, South African team. We're excited about getting going, but it's all about Saturday and making sure we deliver on that day."
Heyneke Meyer: "Believe it or not, you are going to lose games even if you are playing for South Africa. It was one of those strange games where we won everything except on the scoreboard so that doesn't count for anything But there was no complacency. Ireland are a real quality side and they were unlucky not to beat the All Blacks last year. You just can't play on emotion alone. I don't believe in that."