The draw for the 2013/14 Europa League play-off round is to be made on Friday evening, with Tottenham, Sevilla, Fiorentina and Feyenoord among the big names waiting to learn their fate.
Spurs will also be joined by Premier League rivals Swansea City, although, in accordance with UEFA rules, two sides from the same nation will not meet each other at this stage of the competition.
Turkish club Besiktas have been placed in the draw but their involvement in the competition is subject to ongoing Court of Arbitration for Sport (CAS) hearings regarding match-fixing.
Often derided as a secondary competition to the Champions League, the Europa League produced some thrilling football last season and saw strong performances from three Premier League clubs - Spurs made it to the quarter-final before bowing out to Swiss champions FC Basel; Newcastle United were beaten by eventual finalists Benfica of Portugal; and Chelsea went all the way, beating Sparta Prague, Steaua Bucuresti, Rubin Kazan and Basel on their way to a 2-1 defeat of Benfica in Amsterdam in May.
The Blues will be hoping they will not be forced to defend their title though. Jose Mourinho's men have once again qualified for the Champions League and barring a second consecutive disastrous group stage campaign (unthinkable, really, under the Special One), will probably not be at the Juventus Stadium in Italy on 14 May, 2014.
Where to Watch Live
The draw is scheduled for 12pm BST and will be telecast live on British Eurosport. Click here to follow the draw live online, on UEFA's official website.
A total of 62 teams will feature in the draw, to be held at UEFA's headquarters in Nyon, Switzerland. The teams have been divided into six groups; five of these will have 10 teams and the sixth will have an additional two.
Each group will contain an equal number of seeded and unseeded teams, who will be drawn to face each other in the play-offs. The teams drawn first will play the first leg at home. The matches have been scheduled for 22 and 29 August. The winners will join the seven automatic qualifiers - Wigan Athletic, Valencia, SC Freiburg, Lazio, Vitoria de Guimaraes, Bordeaux and Anzhi Makhachkala in the draw for the group stages.
Tottenham in the Draw
Spurs and Andre Villas-Boas will expect a relatively straightforward path to the group stages. The north London side have ambitions of Champions League football next season and have spent well this summer - Brazilian midfielder Paulinho and Spain international Roberto Soldado are among their imports.
AVB will probably regard FC Slovan Liberec as his toughest test. The Czechs won their domestic championship in 2012 and although they finished third last year, will be the dark horses in Group Six.
Other potential opponents are Swiss club FC Thun, who made an emotional Champions League debut in 2005/06. Incidentally, they faced British opposition back then - losing home and away to Arsenal. And they faced another Premier League club in Stoke City, at this stage in the competition last year; they were hammered 5-1 on aggregate.
Estonians JK Nomme Kalju, Austrians FC Pasching and Romanians FC Astra join Dinamo Tbilisi of Georgia as other potential opponents but none of these should worry Tottenham.
Swansea City in the Draw
The Swans return to the European stage after a 20-year break and they're going about it the right way. Michael Laudrup's men dispatched Swedish club Malmo 4-0 on aggregate and, like Spurs, have been drawn in a group that should virtually guarantee an appearance in the group stages.
One side will worry Laudrup though. The former Real Madrid and Barcelona star will have an eye on Greek side Atromitos, who only narrowly lost to Newcastle last season. Furthermore, they finished third in their championship last year, meaning they are still a top side.
The rest of Group Two is (or should be) easy enough, with Cyprus' Apollon Limassol, Kazakhstan's FC Aktobe, Iceland's FH Hafnarfjördur and Romania's FC Petrolul Ploieşti in the pot.