As expected, Manchester City got through a bruising encounter with Stoke City in the early kick-off, though it took a late Pablo Zabaleta goal to do it.
Shock of the day, or cupset if you will, was League One team MK Dons' 4-2 thrashing of Queens Park Rangers at Loftus Road.
Manchester United face Fulham in the evening kick-off.
Highlights of all games are on ITV at 11pm GMT.
Stoke City 0-1 Manchester City (Zabaleta, 84mins) (12.45pm KO) FT
Bolton (Sordell, 28mins) 1 -2 Everton (Pienaar, 19mins; Heitinga, 90mins)
Brighton (Ashley Barnes, 33mins; Ulloa, 65mins) 2-3 Arsenal (Giroud, 17mins, 60mins; Walcott, 86mins)
Derby 0-3 Blackburn (Kazim-Richards, 45mins; Dann, 66mins; Rhodes, 71mins )
Huddersfield (Novak, 74mins) 1-0 Leicester City
Hull 0-1 Barnsley (Dagnall, 75mins)
Macclesfield 0-1 Wigan (Gomez, 6mins, pen)
Middlesbrough (Jutkiewicz, 83mins, 90+5mins) 2-1 Aldershot (Hylton, 85mins
Norwich 0-1 Luton (Rendell, 82mins)
QPR(Bothroyd, 83mins; Fabio, 87mins) 2-4 MK Dons (Lewington, 4mins; Lowe, 40mins; Harley, 50mins; Potter, 56mins)
Reading (Hunt, 7mins; Leigertwood, 40mins; Hunt, 50mins; McCleary, 54mins) 4-0 Sheffield Utd