Adnan Januzaj and Bastian Schweinsteiger look set to leave Manchester United this summer after they were left out of the squad that faced Galatasaray in a pre-season friendly in Gothenburg on 30 July.
Goals from Zlatan Ibrahimovic, Wayne Rooney (two), Marouane Fellaini and Juan Mata gave Jose Mourinho's side a 5-2 victory over the Turkish club, one week before the Community Shield curtain-raiser against Leicester City at Wembley.
Speaking to MUTV after the match, Mourinho suggested that those who were not part of his squad in Sweden would continue their careers elsewhere next season.
Midfielders Schweinsteiger and Andreas Pereira, forwards Januzaj, Will Keane and James Wilson and defenders Cameron Borthwick-Jackson, Timothy Fosu-Mensah, Tyler Blackett and Paddy McNair were all excluded from the 23-man squad for the Galatasaray match.
"If they were not in my plans I would not give them one single minute. I wouldn't keep them in my squad," Mourinho said.
"The squad is very competitive, the squad is very important for the season.
"The other day I was telling them we have 38 matches in the Premier League, we have the possibility of 15 matches in the Europa League plus the domestic cups. We are going to play 60 matches and you cannot do that with 11 players.
"To be in the squad you have to understand that the squad is more important than the individual, the club is more important than all of us and to be in the squad you have to be ready for this: to play, not to play, play a lot, play less, play 90 minutes, play one minute, not be selected," the former Chelsea and Real Madrid boss continued.
"Everything is part of squad life. And when you want to be in a big club like we are, the club is much more important than us."
United, who continue to be linked with a world record deal to sign Paul Pogba from Juventus, next face Everton in Wayne Rooney's testimonial at Old Trafford on 3 August.