Jordan Henderson has added to Liverpool's injury woes after England manager Roy Hodgson confirmed the midfielder's omission from England's friendly win over Scotland was due to a minor hamstring problem.
Henderson, 24, was left out as a precaution from England's 3-1 win at Celtic Park due to the problem.
"Jordan has a slight hamstring problem," Hodgson said. "It is very minor. He wanted to play but I didn't want to take the risk."
Henderson is now a doubt for Sunday's visit to Crystal Palace, the scene of Liverpool's collapse in last season's title race.
Liverpool were left reeling on Tuesday after Daniel Sturridge suffered a fresh setback in his bid to return to first team action.
Sturridge, 25, has not played for the club since the end of August after picking up a thigh injury while on international duty. His comeback was delayed in October due to a separate calf problem, but the England international had been expected to make his return at Selhurst Park this weekend.
However, widespread reports on Tuesday evening suggest Sturridge has suffered a recurrence of the original thigh problem, a development which will act as a sizeable blow to Brendan Rodgers' plans.
Sturridge, who netted 21 league goals last season, has not played for the club since the 3-0 win over Tottenham Hotspur on 31 August. During his absence, Liverpool's other three forward options of Mario Balotelli, Rickie Lambert and Fabio Borini have failed to contribute a single league goal between them.
Balotelli fitness ahead of the visit to Palace is also a concern for Rodgers after the Italian international returned to from international duty early last Friday with a hamstring problem.
Defenders Mamadou Sakho and Jon Flanagan also remain unavailable due to respective thigh and knee injuries.