Manchester United travel to Tottenham Hotspur as the defending Champions look to sustain their title defence this season.
Where to Watch Live
Kick-off is set for 12pm GMT. Live coverage will be available on BT Sport 1 and BT Sport 1 HD.
Tottenham Hotspur come into the game on the back of an ignominious 6-0 loss to Manchester City at the Etihad Stadium last weekend, a result that rocked Spurs after their massive spend last summer.
The north London club has scored only nine goals in the Premier league and from having the best defence in the league, is now faced with a negative goal difference.
The loss has turned the fans against manager Andre Villas-Boas, who called last week's game embarrassing and will be looking to prove his detractors wrong with a solid performance against the defending champions.
Talks have already started over his successor and AVB must liven his team up or fear seeing their top four challenge wither away, only 13 games played.
Manchester United have not been at their best in the league this season, with the Red Devils capping a 1-0 win over league leaders Arsenal at Old Trafford with a tame 2-2 draw against Cardiff.
However, David Moyes will take heart from their midweek performance against Bayer Leverkusen where they annihilated the club that is currently second in the German Bundesliga 5-0, on their own ground.
The team have the personnel to fight for the title but it has been their inconsistency that has cost them dear.
A loss here would leave United 10 points adrift of Arsenal in the table and damage their chances of defending the league title.
What the Managers Say
Andre Villas-Boas: "It is important to recognise that we play the champions and they are on a good run. With such an impressive performance it can only be good for them. We don't expect an easy match. I suppose that they are (not) the best to play after City, but that is what the calendar says. Whoever we play we have to bounce back. The players will be mentally ready."
David Moyes: When you enter the football management business you expect it. Sir Alex (Ferguson) was so successful because he won more than most. But there is no way you can win all the time. It is impossible. There are always going to be down days in football. You have to be able to deal with them and work through them. I am sure Andre will do it because he is a good coach."
- Last Five (all competitions, most recent first): W L L W D
- Last Result: Tromso 0-2 Tottenham
- Last Five (all competitions, most recent first): W D W D W
- Last Result: Bayer Leverkusen 0-5 Manchester United
- Injured: Christian Eriksen(knee), Danny Rose(knee), Harry kane(back)
- Doubtful: N/A
- Suspended: N/A
Probable Line-Up: Lloris; Walker, Dawson, Chiriches, Vertonghen; Sandro; Dembélé, Paulinho; Lennon, Soldado, Lamela.
- Injured: Michael Carrick (Achilles), Darren Fletcher (illness).
- Doubtful: Robin van Persie(groin)
- Suspended: N/A
Probable Line-Up: De Gea; Smalling, Vidic, Evans, Evra; Jones, Giggsi; Valencia, Kagawa, Young; Rooney