Wayne Rooney
Wayne Rooney is likely to start in the more advanced role against Southampton on Sunday.Getty

Manchester United will take on Southampton in the weekend Premier League clash at Old Trafford on Sunday.

Where to Watch Live

Kick-off is at 4pm GMT. Live coverage is on Sky Sports 1 and Sky Sports 1 HD. Radio commentary of the game will be available on BBC Radio 5 Live. Catch the highlights of the game on Match of the Day 2 on BBC One and BBC One HD at 10:30pm GMT.

Overview

United have progressed to the fourth round of the FA Cup after sealing a 2-0 victory over Yeovil Town in the previous round last weekend. On New Year's Day, the 20-times English champions were forced to come from behind to settle for a draw against Stoke City.

It was Radamel Falcao's goal that saved Louis van Gaal's side avoid defeat and also keep their unbeaten streak alive. Since their 1-0 defeat at the hands of Manchester City in November, United have not lost a game in all competitions.

The Dutchman will be hoping his side can maintain the unbeaten run against Southampton on Sunday.

Nathaniel Clyne
Nathaniel Clyne has been linked with a move to United next summer.Getty Images/Steve Bardens

Meanwhile, the Saints settled for a 1-1 draw against Ipswich Town in the third round FA Cup fixture. The cup tie was after they comfortably defeated Arsenal 2-0 at home on New Year's Day.

Ronald Koeman has already seen his side suffer a 2-1 defeat at the hands of United at St Mary's Stadium. At Old Trafford, United have been a dominating team, having lost just one game this season.

The Southampton manager will be aware of the tough challenge his side will face when they take on United in front of their home fans this weekend. The Red Devils are third in the table with 37 points, one point ahead of fourth place Southampton.

What Managers Say

Louis van Gaal: "My ambition is that I have the best players who can collaborate with each other to form the best team of the world. I hope so because, now the players are coming back, I have a full selection of players within three weeks I think."

Ronald Koeman: "It's a quality of [United] that they don't need a lot of shots on target to score two goals and to win games and, if you analyse them in the last few weeks, you can see that they [have] grown up, the players have more confidence in the system, they have less injuries than they had before."

Betting Odds (888Sport.com)

  • Manchester United to win: 9/11
  • Draw: 13/5
  • Southampton to win: 7/2

Team Form

Manchester United

  • Last Five (all competitions): D W D D W
  • Last Result: Yeovil Town 0-2 Manchester United

Southampton

  • Last Five (all competitions): W W D W D
  • Last Result: Southampton 1-1 Ipswich Town

Team News

Louis van Gaal
Louis van Gaal has only one player injured for the Southampton clash.Getty Images

Manchester United

  • Injured: Ashley Young (hamstring)
  • Doubtful: N/A
  • Suspended: N/A

Possible XI: De Gea; Jones, Smalling, Evans; Shaw, Carrick, Blind, Di Maria; Rooney; Van Persie, Falcao

Southampton

  • Injured: Jack Cork (ankle), Sadio Mane (calf), Jay Rodriguez (knee)
  • Doubtful: Nathaniel Clyne (ankle), Sam Gallagher (knee)
  • Suspended: N/A

Possible XI: Forster; Alderweireld, Fonte, Clyne, Bertrand; Wanyama, Davis, Ward-Prowse; Tadic, Elia; Pelle