Sir Alex Ferguson takes his men to Loftus Road as Manchester United face Queens Park Rangers in the Premier League. United won the reverse fixture 3-1 in November.
Where to Follow
Kick-off is set for 3pm GMT. Live radio commentary will be available on BBC Radio 5 Live. Catch highlights of the game on BBC One and BBC One HD at 10.20pm GMT.
Harry Redknapp has a lot to do if the Rangers are to avoid relegation, with less than three months left in the season. QPR are bottom of the table with only 17 points from 26 games so far; Aston Villa are the team teetering on the brink of the relegation zone, and Paul Lambert's side are a full seven points away.
QPR have not played since the 4-1 hammering at the Liberty Stadium in Wales, having been eliminated from the FA Cup by MK Dons in January. This could play to Redknapp's advantage... his side will be fresher and in better physical condition than United, particularly since Ferguson is still competing for the Premier League, the Champions League and the FA Cup. And with the second leg of a Champions League knock-out tie, against Real Madrid, still to come, this could be the perfect time to play the Old Trafford club.
Unfortunately, as their points tally suggests, Rangers have been extremely poor all season and their home form is easily the worst in the league. They've won only once in 13 games and have scored only once. Redknapp's team has lost five of the last seven games at home, in all competitions.
The good news, though, is that QPR have the best home defensive record of any side in the bottom three. Visiting sides have scored a total of 19 goals at Loftus Road, compared to 27 at the DW Stadium and 24 at the Madejski.
There is a bit more good news - Redknapp's men played defending champions Manchester City late last month and held them to a goalless draw. Earlier in January, they held Spurs to a similar stalemate. In fact, four of the top five sides in the league have failed to win at Loftus Road this season.
Nevertheless, United should be confident of victory.
The Red Devils travel after a hard-fought 2-1 win in the fifth round of the FA Cup. Portuguese international Nani came off the bench to set up the win for Ferguson and, in the process, earn himself a lifeline to remain at Old Trafford.
United have been imperious in the league this season and lead City by 12 points and because Roberto Mancini's men play on Sunday, this is an excellent opportunity to turn the pressure up on their rivals.
The leaders have won nine of 13 games on the road this season, with an impressive 28 goals scored. Expect strong resistance from January signing Christopher Samba and Rangers, but Robin van Persie is likely to have far too much to be kept quiet for 90 minutes.
United have not lost a game, in any competition, since Romanians CFR Cluj surprised them in a Champions League group stage match... back in early December.
Queens Park Rangers
- Last Five (all competitions, most recent first): L D D L D
- Last Result: Swansea City 4 - 1 Queens Park Rangers
- Last Five (all competitions, most recent first): W D W W W
- Last Result: Manchester United 2 - 1 Reading
The good news is a number of first team players will return from injury, including high-profile January signing Loic Remy (groin). On-loan United defender Fabio (hip), forward Junior Hoilett (hamstring) and goalkeeper Julio Cesar (groin) are all available and striker Bobby Zamora is also likely to play. Ex-Real Madrid midfielder Esteban Granero, Andros Townsend and Jermaine Jenas add to a strong midfield for the home side.
However, Redknapp will be without ex-Chelsea right-back Jose Bosingwa (back) and striker Andrew Johnson (knee).
Probable Line-Up: Cesar; Fabio, Hill, Samba, Traore; Derry, M'Bia; Hoilett, Taarabt, Wright-Phillips; Mackie
United will be without defender Phil Jones and striker Wayne Rooney but Ferguson has confirmed veteran midfielder Paul Scholes could play a role. Nani's performance against Reading should mean the 26-year-old is given a start at Loftus Road, with Ecuadorian Antonio Valencia dropping to the bench. The second striker's role will be a choice between Javier Hernandez and Danny Welbeck... expect the latter to get the nod.
Probable Line Up: De Gea; Rafael, Smalling, Vidić, Evra; Nani, Carrick, Cleverley, Young; Welbeck, Van Persie