Parts of North Texas were left unrecognisable after 16 tornadoes hit the state on Wednesday night killing at least six people and leaving dozens injured.

In the aftermath of the natural disaster, the affected regions saw hundreds of people left homeless while emergency responders were still searching for missing people on Thursday afternoon.

The city of Granbury, which lies about 60 kilometres southwest of Fort Worth, was one of the worst hit regions in the calamity, with wind speeds between 267km/h and 320km/h, according to the National Weather Service. Other badly affected areas included Cleburne and Hood County.

On Thursday authorities searched through debris in the affected areas while residents, who were left homeless overnight, waited to see the remains of their houses and properties.

"I tell you, it has just broken my heart," Habitat for Humanity volunteer Elsie Tallant told ABC News.

Hood County Commissioner Steve Berry on Thursday said that the destruction was so massive he couldn't tell one street from another in Granbury's Rancho Brazos Estates neighborhood.

Describing the search operation for bodies in Granbury, Sheriff Roger Deeds said: "Some were found in houses. Some were found around houses. There was a report that two of these people that they found were not even near their homes. So we're going to have to search the area out there."

Following the disaster, 20,000 homes and businesses in the area were left without power early on Thursday.

Scroll down to see the condition of the affected areas in the aftermath of the calamity.

A trailer blown into a home on Lindsay Lane in Cleburne rests on a car after a tornado touch down in Cleburne, Texas May 16, 2013.REUTERS/Richard Rodriguez
Pete Alaniz assesses the damage to the garage of his rental home that was destroyed by a tornado in Cleburne, Texas May 16, 2013.REUTERS/Richard Rodriguez
A damaged home and car remain May 16 after tornados swept through the town of Granbury, Texas late May 15, 2013REUTERS
A rescue worker combs through debris May 16 after tornados swept through the town of Granbury, Texas late May 15, 2013.REUTERS
An aerial view shows the damage after tornados swept through Hood County, Texas May 16, 2013.REUTERS
A home is left damaged after it was struck by a tornado in this aerial photograph taken in Cleburne, Texas on May 16, 2013.REUTERS
A man walks towards a metal container which struck Lowell Smith Junior Middle School, after the area was hit by a tornado in this aerial photograph taken in Cleburne, Texas May 16, 2013.REUTERS
Rescue workers search a home after it was left flattened by a tornado in this aerial photograph taken over Granbury, Texas on May 16, 2013.REUTERS
Security officials, media and residents surround homes damaged by a tornado in this aerial photograph taken over in Cleburne, Texas May 16, 2013.REUTERS
An aerial view shows the damage after tornados swept through Hood County, Texas May 16, 2013.REUTERS
An aerial view shows the damage after tornados swept through Hood County, Texas May 16, 2013.REUTERS