Danny Rose
Rose set for Tottenham comeback but AVB still has defensive headaches. (Reuters)

Danny Rose looks to be ready and raring to go ahead of Tottenham's Europa League clash with Anzhi Makhachkala on Thursday night.

Following almost three months out of the game with a toe injury, the Spurs defender was spotted training with the first-team squad in preparation for their upcoming tie at White Hart Lane.

The Portuguese coach later confirmed that the full back will have some role to play in Thursday evening's game. "We will also look to give Danny Rose a couple of minutes in this game after his three-and-a-half month absence," he told reports, via London 24.

Rose looks likely to replace the out-of-position Jan Vertonghen who had been holding fort at left-back in his absence. The Belgian international meanwhile has been ruled out for the next four weeks with an ankle injury.

Bottom-of-the-group Russian Premier League team Anzhi have too suffered injury to their side in the run up to their London visit, prompting expectations that Spurs manager Andre Villas-Boas will give some of his fringe players a run-out.

Tottenham meanwhile have already won Group K.

Despite Rose's return, Villas-Boas is still beset by fitness problems in his squad. The Spurs boss confirmed Vertonghen has suffered ankle ligament damage in his pre-match press conference on Thursday afternoon, also revealing that Younes Kaboul is still struggling to regain full fitness after a string of setbacks following a long term knee injury last season.

"At the moment there is obviously ankle ligament damage [for Vertonghen]," the Spurs boss added. "We will have the player in a boot for one to two weeks to try to settle it.

We want to avoid surgery so we will use PRP [blood-spinning] treatment to try to get him back as soon as possible. We've had outstanding results with PRP treatment and we will do that again now.

"Younes was supposed to be back in training but he had a small setback - but he should be back on Tuesday for training.

"It's obviously a concern but there's nothing we can do. Our conclusion is that, given the amount of injuries he has on his knees, his body is constantly adapting to new positions and straining muscles here and there.

"We have to be patient with him, trying to build him muscle-wise, and hopefully we can have him back."