Sam Allardyce takes his West Ham side to White Hart Lane, where the Hammers will look to continue what has been a spectacular start to life in the Premier League. The newly promoted club are seventh in the league and lead Andre Villas-Boas' more fancied outfit by two points going into this game.
West Ham are seventh in the table, with 19 points and five wins from 12 games; Spurs are eighth with 17. The weekend fixture marks the return of referee Mark Clattenburg, as a fourth official, after the 37-year-old was cleared by the FA of alleged racist conduct in Chelsea's clash against Manchester United on 28 October.
Where to Watch Live
Kick-off is set for 4pm GMT. Watch highlights of the game on Match of the Day on BBC One and BBC One HD at 10.25pm GMT.
Spurs come into the game with just one win in their last five league fixtures... and the last was a miserable 2-5 north London derby defeat to Arsenal. AVB will expect nothing less than all three points on Sunday, particularly against a side which, on paper, should be an easy opponent.
Tottenham's midweek game was not a particularly favourable result either, with the London club only just holding Italian side Lazio to a draw at the Stadio Olimpico. The match in Rome was marred by a violent attack on travelling Spurs fans and that will be another reason why the club should look for a strong winning statement of support for their supporters.
Spurs do have a measure of history on their side. They have not lost three home games in a row (in the league) since September 2008, and have won seven of eight league games against West Ham. Better still, the Hammers have failed to score in five of those seven games.
However, regardless of that history, Tottenham will have to improve on recent performances. AVB's side have won only two of six home games in the league, conceding eight goals in those fixtures. Moreover, the last time they won a Premier League fixture at home was back in the first week of October, when they beat Villa 2-0. Since then, they have lost two of three games and both defeats were in the league.
West Ham, meanwhile, are clearly enjoying themselves... and with the experience of Allardyce behind them, expect them to fight not only against relegation but - on current form - perhaps even for a European spot. The club drew their last game - at home to Stoke - and before that emerged with four points from a possible six, with a home draw against the champions Manchester City and an away win at Newcastle United.
Prior to the Stoke draw and the win against Newcastle, Allardyce's men recorded a 4-1 home win against Southampton and beat QPR at Loftus Road, to mitigate the impact of defeats to Arsenal and Wigan Athletic. On the whole, the club has had a reasonably strong last few weeks.
The big advantage in favour of the visitors for this game will be freshness. West Ham have played only once every seven or eight days since October (not including international breaks) and will certainly be the fitter and fresher squad. Spurs, meanwhile, must contend with fatigue after returning from Rome and their Europa League game on Thursday.
- Last Five (all competitions, most recent first): D L L W L
- Last Match: Lazio 0 - 0 Tottenham
West Ham United
- Last Five (all competitions, most recent first): D W D L W
- Last Match: West Ham United 1 - 1 Stoke City
The hosts will be without defenders Younes Kaboul and Benoit Assou-Ekotto for this game, both of whom remain unavailable with long-term injuries. England midfielder Scott Parker has returned to light training following his injury but is unlikely to play this match.
Meanwhile, AVB will recall another England player in Jermain Defoe to the striker's role, after fielding Togo international Emmanuel Adebayor in Rome. The ex-Arsenal and City forward will now begin a three-match suspension for a red card in the last league game.
There are, otherwise, no real concerns for Spurs. Expect French captain Hugo Lloris to retain his place in goal for this game, after a Man of the Match performance in midweek. Last season's PFA Young Player of the Year, Kyle Walker, will line up at right back, with Steven Caulker and Michael Dawson in central defence and summer signing Jan Vertonghen at left back.
The good news further up the field is Vertonghen's international team mate, Moussa Demeble, has recovered from his injury and is likely to start this game, meaning Tom Huddlestone drops to the bench. The attacking trio of Aaron Lennon, Clint Dempsey and Gareth Bale will provide width and creativity.
Probable Line-Up: Lloris; Walker, Caulker, Dawson, Vertonghen; Dembele, Sandro; Lennon, Dempsey, Bale; Defoe
As for West Ham, Allardyce will only have to worry about former Chelsea winger Yossi Benayoun. The Israeli has recovered from a knee injury but may not be risked from the start. Other injuries for the squad are Alou Diarra, Ricardo Vaz Te and Jack Collison. Midfielder Matt Jarvis will return from his injury but will probably have to settle for a bench role for this game, with both Modibo Maiga and Gary O'Neil impressing in the game against Stoke.
Probable Line-Up: Jaaskelainen; O'Brien, Reid, Tomkins, McCartney; Noble, Nolan, O'Neil, Maiga; Diame; Carroll