Tottenham left-back Danny Rose has been the latest England international to be pulled out of Roy Hodgson's squad to face Lithuania and Italy due to an injury.
The Spurs defender is the fifth player forced to leave the squad earlier than expected after Manchester United starlet Luke Shaw, Southampton goalkeeper Fraser Forster, and Liverpool duo Daniel Sturridge and Adam Lallana were previously withdrawn from the European Championship qualifier with Lithuania at Wembley on Friday, 27 March.
Hodgson is also reportedly expected to let some more player's, including Raheem Sterling, to miss the trip to Turin to face Italy on 31 March.
Rose was on line to make his full England debut after just on Saturday being called up to replace Luke Shaw, who also suffered an injury. However, the FA have confirmed the Spurs star has also been sent back to his club due to an injury.
"Tottenham Hotspur defender Danny Rose has withdrawn from the England squad through injury," the FA announced.
"The left-back will play no further part in preparation for the forthcoming fixtures against Lithuania and Italy and has returned to his club."
Hodgson will not call a replacement as despite Rose's absence still has Everton's Leighton Baines and Arsenal's Kieran Gibbs to fill the void.
The manager also previously decided against replacing Sturridge while QPR goalkeeper Rob Green and Jack Butland of Stoke City were called up to replace Southampton's Forster.
Furthermore, Rose's teammate Ryan Mason was included in the England squad for the first time in his career as a replacement for Liverpool star Lallana. Neither the FA nor Tottenham have confirmed the length of Rose's injury, meaning his availability for the next Spurs Premier League game against Burnley on 5 April is uncertain.