After qualifying for the last 16 of the Champions League as winners of a group that contained holders Real Madrid and one of Germany's finest in Borussia Dortmund, much attention will be paid to Tottenham Hotspur, who made it through to the knockout stages of Europe's premier club competition in impressive fashion.
Mauricio Pochettino's side were set an almighty challenge when they were pitted against Real, Dortmund and the less-fancied Apoel Nicosia, but they managed to sweep aside Los Blancos, BVB and The Legend to secure their passage to last 16 unbeaten, with a game to spare.
Entering the draw as group winners has its advantages, but Tottenham, who have stuttered in the Premier League in recent weeks and are now closer to bottom club Swansea City than runaway leaders Manchester City, will still have to face one of Europe's most notable sides, with some of continent's elite potentially lying in wait.
When and where is the last 16 draw?
The draw begins at 12:00CET on Monday 11 December and will take place at UEFA headquarters in Nyon, Switzerland.
Best case scenario: Basel
The Swiss champions may be able to boast a decent enough record against English sides both in the Champions League and Europa League - they have emerged victorious over Manchester United and Chelsea in recent years, their most recent scalp coming against Jose Mourinho's side in the penultimate round of this season's group stage - but the Swiss champions do not seem capable of intimidating opponents like they did when they were relative unknowns on club football's biggest stage.
Raphael Wicky's men were perhaps a tad fortunate to be pitted in a group which contained an ordinary CSKA Moscow and a hapless Benfica, who failed to earn a single point during their ill-fated European campaign, but they still needed a fortuitous win against United who should have been out of sight in the first half of the clash at St Jakob-Park a fortnight ago.
Attackers Mohamed Elyounoussi and Dimitri Oberlin have the talent and speed to threaten most defences, but on the whole Basel do not seem capable of troubling Tottenham or any of their esteemed counterparts, who will all be hoping to be pitted against the Swiss giants when the draw takes place on Monday.
Worst case scenario: Juventus
Tottenham are not able to face Real Madrid in the last 16 having just faced them twice in the group stage, but they could still have to face a European heavyweight if luck doesn't favour them in Nyon.
Juventus and Bayern Munich both finished behind Barcelona and Paris Saint-Germain in their respective groups, but while the Italian and German champions have had their troubles during the beginning of this season they will still provide formidable opposition for Tottenham, who actually managed to beat Juve 2-0 in a pre-season friendly in August.
Last season's beaten finalists and the dominant force in Serie A for so long, Juventus have certainly not had things their own way during the beginning of the current campaign. Massimiliano Allegri's men were pushed hard by Sporting Lisbon for second place in Group D and currently find themselves in the perhaps unfamiliar position of third in Serie A, two points behind a resurgent Inter Milan in first.
For all their attacking talent Juve only managed to score seven goals in the group stage, but their recent victory over fellow title contenders Napoli last weekend may prove to be the catalyst for a change in fortunes. Gonzalo Higuain's first-half strike handed his side a priceless victory against his former club, who are playing some of the best football on the continent under Mauricio Sarri.
The Bianconeri will also go into the last 16 refreshed from their rearranged winter break, which will end on 21 January after all of Serie A's clubs decided to move it from December. The mid-season rest will allow the likes of Paulo Dybala to recharge ahead of a tantalising second half of the campaign; the Argentine started the season in tremendous form but his productivity has dropped off severely in recent weeks. 'The Jewel' is pivotal to Juve's fortunes but is certainly not the only matchwinner in Allegri's arsenal, with Higuain, Douglas Costa, Mario Mandzukic and Juan Cuadrado all capable of exploiting the meanest of defences.
Spurs have fond memories of playing Italian giants in the knockout stages of the Champions League - Harry Redknapp's side managed to down a declining AC Milan in the last 16 of the tournament in 2011 - but they will hope a trip to Turin is not on the cards in the New Year.