Deutsche Bank is to slash the majority of its global commodity units because of regulatory pressures.
The lender disclosed it will quit energy, agriculture, base metals and dry bulk trading.
The move will result in the loss of 200 jobs, according to Reuters.
The German bank said it will focus on its core competencies of financial derivatives and precious metals.
"The decision to refocus our commodities business is based on our identification of more attractive ways to deploy our capital and balance sheet resources," said Colin Fan, co-head of corporate banking and securities at Deutsche Bank.
He added: "This move responds to industry-wide regulatory change and will also reduce the complexity of our business."
The lender said a special commodities group has been established which will manage an "orderly wind down" of the businesses.
In addition, the bank will integrate the financial derivatives and precious metals businesses into its fixed income and currencies platform.
The move comes as the financial sector's role in commodity trading has been squeezed by growing regulatory scrutiny.