Around seven out of ten (71%) of employers have spotted a lie on a CV and as a result 41% have discarded that candidate, according to CareerBuilder.
The jobs site added that only around 6% of the respondents said they would be willing to overlook a lie if they liked the candidate.
"Trust is very important in professional relationships, and by lying on your CV, you breach that trust from the very outset," said Rosemary Haefner, vice president of human resources at CareerBuilder.
"If you want to enhance your CV it is better to focus on highlighting tangible examples from your actual experience.
"Your CV doesn't necessarily have to be the perfect fit for an organisation, but it needs to be relevant and most importantly accurate."
The research also revealed that embellished skill sets and embellished responsibilities (both 57%) were the most common CV lies and dates of employment was the second most popular fabrication (40%).
The report also found that employers may now be taking more time to look over individual CVs, with half of employers (51%) saying they spent more than two minutes reviewing each CV.
However, 25% of employers spent less than 60 seconds and 12% said they spent 30 seconds or less on each CV.