Air Algerie flight AH5017, flying from Ouagadougou in Burkina Faso to Algiers, has lost contact with the air traffic control and remained untraceable several hours after its scheduled time of arrival at destination.
The aircraft reportedly lost contact 50 minutes after take-off.
"In keeping with procedures, Air Algerie has launched its emergency plan," the airline said, according to Algeria's APS news agency.
"Air navigation services have lost contact with an Air Algerie plane Thursday flying from Ouagadougou to Algiers, 50 minutes after takeoff," the airline stated.
Spanish airline Swiftair, which operated the flight chartered by Air Algerie, has said there were 110 passengers and six crew members aboard the aircraft, Reuters reported.
The air route between Ougadougou to Algiers is nearly a straight line, overflying Mali, which is facing political unrest.
While the plane remains missing, the social network has been flooded with anxious comments from people who fear this could be the third major flight mishap within a week, following the Malaysia Airlines flight MH17 crash and Taiwan's TransAsia accident.
Here are some of the anxious tweets:
Air Malaysia x2 (crashs dans l'océan Indien + Ukraine), TransAsia (crash à Taïwan), Air Algérie (crash probable au Mali)... loi des séries ?
— Delphin DRUELLE (@delphindruelle) July 24, 2014
Air Algerie has been missing for 6 hours. 110 passengers and 6 crew. Flying is now turning into horror stories. #AH5017
— SAMUEL KING (@xsamuelking) July 24, 2014
Another missing plane RT @AP BREAKING: Owner of missing plane operated by Air Algerie says 110 passengers and 6 crew were aboard.
— Olivia Goldhill (@OliviaGoldhill) July 24, 2014
ONE MORE! FRIGGIN UNBELIEVABLE! Air Algerie — @v@ntik@ (@stunningmoon) July 24, 2014
So the Air Algerie flight has reportedly crashed
— Ramanathan S (@madarassi) July 24, 2014