The newly married couple, who have not been formally identified, were travelling in a Suzuki Ignis towards Scarborough and the HGV lorry was travelling in the opposite direct when they collided at around 3.40pm on Friday (22 July).
Joy and Derek Green, their wedding guests, died at the scene of the accident, according to their daughter Melanie Ann Green, who posted a Facebook tribute saying it was "the worst day of my life".
The post read: "I know a great many people loved my parents, they were amazing, wonderful, weird people, they opened their hearts to the entire world. They were my world.
"I know a lot of people will want to call and offer help.
"I just ask that for now you respect our grief and our privacy and please be patient with us while we go through this difficult time.
"Thank you to everyone who has reached out to me and my sister Tammy and partner John today and in the days to come."
Green named the deceased newlyweds as her "Uncle Paul and his partner Sue", who were in the back of the car when the crash happened.
The couples were coming back from the wedding which took place in Leeds, she said. She asked people "to respect our grief and our privacy".
Traffic Sgt Paul Cording, of North Yorkshire Police, described the scene of the accdient as "the carnage of a very serious road traffic collision".
A spokeswoman for North Yorkshire Police said: "All three emergency services were called to the scene including the fire and rescue service, road ambulance and air ambulance.
"The road was closed in both directions to allow emergency services to deal with the collision and to allow collision investigators to examine the scene. It reopened early the next day."
The 26-year-old driver of the HGV was unhurt.