Full-time: Hull 1-3 Arsenal
Arsenal are now only third behind Manchester City by virtue of a slightly inferior goal difference and have a game-in-hand over their top-four rivals to be played against Sunderland later this month.
That second-half goal from Quinn means that Hull's goal difference is now equal to that of Leicester but they drop to 17th anyway as they have scored six goals less than the Foxes so far this season.
Next for Arsenal is a home fixture against Garry Monk's Swansea on 11 May, while Hull continue their quest for survival with a winnable home clash against rock-bottom Burnley.
That is it for this live blog, thanks for joining us. Goodnight.
A comfortable win for Arsenal, then, who have now scored more than 100 goals this season.
They were at their vintage best at times in the first half as a Hull side curiously lethargic after two impressive wins struggled to cope with their pace, passing and quality of movement.
The hosts were far more resilient after the break, however, and had chances to make it a more uncomfortable ending for Wenger's side who could perhaps be accused of letting their foot of the gas a little too quickly.
Ultimately, Bruce will probably be content with six points from tricky ties against Crystal Palace, Liverpool and Arsenal, but with Leicester and Sunderland both winning this weekend, the margin for error at the bottom of the table is preciously thin from here on out.
Hull 1-3 Arsenal
Walcott sends a shot wide for Arsenal before they launch another attack courtesy of Cazorla.
This time it's Sanchez who runs at Dawson looking for his hat-trick, but his shot is dragged wide of Harper's right-hand post after Walcott had created a useful diversion.
Four minutes of added time signalled. Hull have made a relatively decent fist of this after a dismal first half, but surely a draw is now beyond them bar an eventful finish.
Theo Walcott is summoned by Wenger and comes on for Giroud.
Arsenal push forward through Bellerin, who combines well with Sanchez on the right before running onto a pass from Giroud. His shot is parried by Harper.
Wilshere's strike on the rebound is then blocked by what looked like a hand and Sanchez hits the side netting from a difficult angle.
Jelavic enters the fray at the expense of Hull goalscorer Quinn. There 10 minutes left for the Croatian striker to make a significant impact.
Meyler is now back on after that nasty wound is quickly patched up.
Cazorla has looked terrific for Arsenal tonight, yet he cannot add his name to the list of scorers after his volley from Ozil's cross is comfortably saved.
Sanchez's free-kick is deflected once more, but this time does not trouble Harper.
Hull fans were incensed that referee Lee Mason did not stop play before Wilshere's run after Meyler sustained a head injury following a coming together with Koscielny.
There is blood pouring from his face.
Encouraging for Arsenal and England fans alike to see Wilshere back after five months on the sidelines with ankle problems.
He has looked good in recent performances for the U21 side and was on the bench for top-flight games against Chelsea and Crystal Palace as well as the FA Cup semi-final against Reading at Wembley.
His first involvement is a surging run at the heart of the Hull backline which earns the Gunners a free-kick after a foul from Dawson.
That was Ramsey's last contribution of the evening as he jogs off to be replaced by Jack Wilshere who is making his first senior appearance since the 2-1 defeat to Manchester United on November 22.
Another chance for Ramsey after a sumptuous flick from Olivier Giroud, but he loses composure at the vital moment and hacks wildly over.
Robertson is on for Hull in place of Aluko.
Hull come desperately close to grabbing another as Paul McShane rises high to power Elmohamady's header inches over the crossbar.
Damage limitation indeed. A real atmosphere builds around the KC Stadium for the first time tonight.
I spoke too soon, clearly, as Hull reduce the deficit. Meyler carries possession forward and the ball bounces to Elmohamady after he is tackled. The Egyptian then crosses for Quinn, who heads past Ospina.
Goal: Hull 1-3 Arsenal (Stephen Quinn)
Damage limitation for Hull already now, you would think. As it stands, they have already dropped below Leicester to 17th on goal difference and at -16 they are only five better off than Sunderland in that regard.
Ramsey looks to make it 4-0 after exchanging passes with Cazorla but his awkward half-volley fails to hit the target.
The second half is now underway. Can Hull prevent a bad evening from getting a whole lot worse? Arsenal have looked rampant and will likely fancy their chances of adding to this healthy lead.
One substitution for Hull, with Meyler returning from suspension to replace Livermore. A 45 minutes to forget for the former Tottenham man, who was booked and cheaply gave away the free-kick that led to the opener.
Excellent from Arsenal. Wenger's side, led by Cazorla and Ramsey, have played some wonderful football in that opening half and Hull simply do not have an answer.
The hosts have had one or two bright moments themselves courtesy of Brady and Elmohamady, but they are yet to test Ospina. They will have to tighten up considerably after the break to avoid humiliation here.
Hull 0-3 Arsenal
Arsenal look unstoppable and they make it three after Ramsey is afforded ample time to find Sanchez, who times his run between the Hull centre-back's to perfection before rounding Harper and firing into an empty net.
No coming back now for the hosts, surely.
Goal: Hull 0-3 Arsenal (Alexis Sanchez)
A fine sequence of passing football from Arsenal involving Cazorla, Ramsey, Sanchez and Ozil ends with German firing tamely at Harper. That was a lovely flowing move and deserved a better finish.
Cazorla then picks out the run of Sanchez with yet another great pass but the former Barcelona forward is thwarted as Harper rushes out to block his attempted chip.
A chance for N'Doye as Huddlestone finds him with a low free-kick but he fires wide with the offside flag raised.
Mertesacker is alert to block an Elmohamady cross and it remains 2-0.