Eric Dier and Danny Rose
Dier and Rose have remained in London ahead of the first leg in DortmundGetty Images

Tottenham Hotspur are without Eric Dier and Danny Rose for the Europa League last-16 first leg against Borussia Dortmund after the pair failed to make the trip with the squad to Germany. Rose suffered from cramp in his calf in the draw with Arsenal while Dier is being rested.

Midfielder Dele Alli is suspended after picking up his second booking of the competition in the last-32 second leg against Fiorentina. The England international was harshly cautioned for diving at White Hart Lane and will not be available until the second leg. Jan Vertonghen and Clinton Njie are also unavailable due to long-term knee injuries.

Despite being without two key players in Rose and Ali, Pochettino is unconcerned and feels his Tottenham squad has the depth to cope with the absentees. "Everything is okay," he told the club's official website. "Now it's all about making the right decision and picking the 11 players to compete in the best way."

With the Premier League title race set to go down to the wire, Tottenham are yet to prove they can juggle domestic and European commitments effectively for a full season. Spurs lost to Crystal Palace in the FA Cup and narrowly defeated Swansea City in the matches that followed the two legs of their last round against Fiorentina, and Pochettino remains unwilling to prioritise one competition over another.

"I think we have a very tough game against Borussia Dortmund and I think the Europa League and Premier League are competitions that are our priority now because we have two competitions," the Tottenham boss told Sky Sports. "But in the same way we are in a period that is tough for the players and sometimes you need to refresh the team and sometimes you need to rotate.

"It is difficult to play every game with the same team and for that, from the beginning of the season, we always spoke about the important thing is to have a big squad and that all the players feel they are important and the starting XI is the best team we can pick to try to win the game."