Four teams will go into the pot in Friday's UEFA Europa League draw to be held in Nyon, Switzerland.
Where to Watch Live
The draw starts at 11:15am BST, with British Eurosport providing live coverage in the UK. Click here to watch the draw live online, via UEFA's official website.
Italian champions Juventus, Portuguese outfit Benfica, along with two Spanish club Sevilla and Valencia made it to the last four of this season's second tier of the European club competition.
The semi-final draw will be open and no teams are seeded. A team can face another team from the same association.
The side drawn first will play the first leg at home. The first leg of the semi-final clash will be played on 24 April, with the return leg being played on 1 May.
Juventus sealed a 3-1 aggregate victory over Lyon to make it to the semi-final of the Europa League. The first leg away from home saw Antonio Conte's side register a 1-0 win away from home. In the return leg, the Italian champions managed a 2-1 victory at home, thus progressing to the last four of the competition.
Benfica had no worries in progressing to the last four as they defeated AZ Alkmaar 3-0 on aggregate. The Portuguese side made it to the final of last season, only to lose to Chelsea in the final minutes of the game.
Benfica would be looking for a win in the two-legged semi-final clash to win the Europa League this season.
The Spanish side defeated FC Porto 4-2 on aggregate. The first leg in Portugal saw the Primeira Liga champions register a 1-0 win. Despite having the advantage, Porto failed to progress as Sevilla had a crushing 4-1 win over their quarter-final opponent in making it to the last four for the Europa League.
Valencia progressed to the semi-final of the second tier of the European club competition after overcoming a 3-0 first leg deficit against FC Basel. The Spanish outfit sealed a 5-0 victory in the home leg, to win the two-legged quarter-final tie 5-3 on aggregate.