Manchester United's troubles have further deepened following reports that Chris Smalling picked up a knock on his thigh during training.
The Red Devils are suffering a major injury crisis in their defensive department and already have two first-team defenders in the medical room and one suspended.
Phil Jones is out with a hamstring injury, Jonny Evans limped out during their shocking 5-3 loss against Leicester City at the weekend and is presumed to be out for at least a month with ankle injury and youngster Tyler Blackett is suspended following his red card against the Foxes.
Smalling, who came on following the injury to Evans, is also just returning from a month-long layoff from a groin injury. But his return did not prevent the King Power Stadium outfit from scoring four goals in 21 minutes.
This will be the last news Louis van Gaal would have wanted ahead of a crucial fixture against West Ham United on Saturday at Old Trafford.
The Hammers are one of the form teams following their victory over Liverpool last weekend and Sam Allardyce will be looking forward to adding another feather in his cap by beating the Red Devils in their own stomping ground.
The Old Trafford club will assess his condition on Thursday and van Gaal will be hoping that he is fit to play at the weekend. If the England international is fit, the Dutchman will have yet another new pairing with Marcos Rojo and Smalling.
Luke Shaw, who has been sidelined with a hamstring injury since his big money move in the summer is surely set to make his debut for the Manchester club at the weekend after spending the last couple of games on the bench.