- Henrikh Mkhitaryan powers home 10th goal of the season after fine pass from Paul Pogba releases Marcus Rashford
- Anderlecht captain Sofiane Hanni nets close-range equaliser shortly past the half-hour mark
- Hosts miss hatful of chances during dominant display after the interval
- Rashford eventually restores United's lead in the second-half of extra-time after executing a superb drag back to create space for a deflected shot that goes in off the fingertips of Ruben Martinez
- Marcos Rojo stretchered off in the first half after a painful clash of knees with Alexandru Chipciu and an attempted tackle on Frank Acheampong
- Zlatan Ibrahimovic limps off at the end of 90 minutes with an apparent knee injury suffered during a horribly awkward landing
- Ajax bounce back from 2-0 deficit in Gelsenkirchen to secure first European semi-final for 20 years
- Pione Sisto's goal in Belgium seals Celta Vigo's maiden last-eight berth
The semi-final lineup is now set. Be sure to join IBTimes UK tomorrow from 10.30 BST for live coverage of both the Champions League and Europa League draws.
We will also have post-match reaction from Mourinho for you at some stage tonight.
Goodbye for now.
Lyon beat Besiktas 7-6 on penalties
Rashford pops up in extra-time with his third goal in four matches to send United through to the semi-finals of the Europa League. What a captivating, breathless second leg packed full of chances and talking points.
United got there in the end, although, having gone in at half-time in 90 minutes all square after an impressive Anderlecht surge, should have made sure of victory much sooner.
Fans will wait nervously for news on those serious-looking knee injuries suffered by Rojo and Ibrahimovic.
End of extra-time
Manchester United 2-1 Anderlecht (Agg 3-2)
Besiktas 2-1 Lyon (Agg 3-3) - match goes to penalties
Schalke 3-2 Ajax (Agg 3-4)
Goal: Schalke 3-2 Ajax (Amin Younes)
Martial slots in Mkhitaryan's pass but is flagged for offside. Mbodji then gets up above Shaw to whistle a header inches over the crossbar.
A couple of scary moments for Romero and the United defence as Anderlecht push forward in search of an equaliser to stun this home crowd.
Romero does just about enough to deny Acheampong after the Ghanaian looks to turn home Mbodji's header. This one is not over just yet.
Incredible drama in Germany. As it stands, Ajax are going through on away goals.
Goal: Schalke 3-1 Ajax (Nick Viergever)
Pogba should wrap up victory, but his shot lacks the requisite power and is palmed away by Ruben.
A long ball from Blind is guided towards Rashford by the head of Fellaini and the academy graduate does fantastically to create a pocket of space for a shot that takes a slight nick off Mbodji and goes in off the fingertips of Ruben.
Relief floods around the Theatre of Dreams. Is that the goal that sends United through to the semi-finals of the Europa League?
Goal: Manchester United 2-1 Anderlecht (Marcus Rashford)
15 minutes away from a penalty shootout in Manchester.
Half-time in extra-time
Manchester United 1-1 Anderlecht (Agg 2-2)
Besiktas 2-1 Lyon (Agg 3-3)
Schalke 3-0 Ajax (Agg 3-2)
Dendocker blocks Rashford's latest effort.
At the other end, Romero spills an awkward left-footed shot from Tielemans but gathers at the second time of asking to stop Thelin from putting Anderlecht in front.
Goal: Schalke 3-0 Ajax (Daniel Caligiuri)
Pogba has the ball in the net but the referee blows for climbing by Fellaini on Spajic.
Still we remain level at 1-1.
Appiah cuts down Rashford near the byline and is promptly shown a yellow card. Rashford's free-kick towards Fellaini is headed away heroically by Spajic.
The Serbian centre-back, currently on loan from Toulouse, has been colossal tonight.
Mkhitaryan glides past Anderlecht's midfield and looks to send Rashford clear. Important clearance from Appiah.
Opportunities at both ends as this breathless encounter shows no signs of slowing down.
Ruben gathers a deflected long-range shot from Mkhitaryan and Obradovic's powerful attempt is diverted behind, seemingly off substitute Thelin.
The referee controversially signals for a corner and Stanciu blazes over.
A cheeky rabona cross from the confident Rashford sets up Pogba for an overhead kick that is blocked by Spajic.
That would have been a sensational goal.
Incredibly, three of tonight's four quarter-final second-leg ties are heading to extra-time.
Yet more injury woe for United as Ibrahimovic limps off after appearing to hyperextend his knee. The stretcher was brought out, but he left the pitch under his own weight.
Martial comes on for the additional 30 minutes.
Genk 1-1 Celta Vigo (Agg 3-4)