Newcastle United fear Yohan Cabaye, Papiss Cisse and Sylvain Marveaux could all leave St James' Park in the January transfer window, according to the Northern Echo.
While refusing to invest in the transfer market owner Mike Ashley has overseen the departure of high profile players such as Andy Carroll and Demba Ba.
Despite an encouraging start to the campaign, with four league wins from their opening 10 games Ashley is again ready to allow several big-name players leave Newcastle.
The highest profile departure is expected to be Cabaye, who was subject of a bid in the region of £11m from Arsenal in the summer transfer window but has returned to first-team action scoring in the games against Everton and Liverpool.
With concerns remaining over the fitness of Abou Diaby and Jack Wilshere, Arsenal are understood to be contemplating a second bid for Cabaye but must match Newcastle's valuation of £20m.
The French midfielder's exit could spark several departures from the north east, with the misfiring Cisse a possible candidate to leave having not scored in the Premier League since April.
The Senegal striker joined from Frieburg in the 2012 January transfer window for a reported £10m and following a whirlwind start to his Toon career has failed to recapture his early form, netting just eight league goals in 35 starts last term.
The third and final loss in January could be out of favour winger Sylvain Marveaux, who has seen Gabriel Obertan leapfrog him in the pecking order in Alan Pardew's side and is being linked with a return to France.
Marveaux joined Newcastle for just £1.5m and having made five appearances this season appears to be surplus to requirements.
Despite the myriad of possible sales, Newcastle fans have grown accustomed to departures not being followed by replacements and following protests regarding the club's ownership the relationship between supporters and the Magpies hierarchy is likely to be tested in the New Year.