Raphael Varane and Karim Benzema both returned to training for Real Madrid on 10 April as the duo close in on a return to first-team action. Benzema suffered a knee injury in the Champions League quarter-final first-leg defeat to Wolfsburg on 6 April and missed the league win over Eibar at the weekend as a result.
Centre-back Varane, meanwhile, picked up a calf problem in training and has missed the Spanish side's last three matches.
The Madrid giants slumped to a shock 2-0 defeat in the first leg in Germany and find themselves in need of a big win in the return leg to keep their Champions League hopes alive.
Real made light of Benzema's absence against Eibar, as James Rodriguez, Lucas Vasquez, Cristiano Ronaldo and Jese all got on the scoresheet to give the hosts a 4-0 win.
That result, coupled with Barcelona's shock defeat at Real Sociedad, means the capital club now trail the La Liga leaders by just four points.
Meanwhile, Ronaldo admitted that Real will have to play to perfect match in midweek to knock out Wolfsburg and progress to the last four of the Champions League.
"Tuesday will be a perfect night, it will be magical, with [the fans'] support us players will give everything on the pitch and we will get through to the next round," he told Real's official website.
"It must be a perfect night. All aspects are important. Those of us on the pitch need to run fight and play with intensity for 90 minutes.
"Obviously, with the fans helping and supporting us it will be easier for us. It is also important to remain calm in certain situations, we need patience and to know how to suffer for the win," the Portugal forward continued.
The key objective is getting through to the next round. It is the only option that will allow us players and the fans to leave the stadium happy."