Tottenham host Leicester City just three days after their gruelling 2-2 encounter at White Hart Lane in the third round of the FA Cup. Harry Kane's penalty in the final minutes of the game forced Leicester into a replay at the King power Stadium, an unwelcome distraction amid a barrage of fixtures for the season's surprise package.
Where to watch live
Kick-off is set for 8pm GMT. Highlights of the game will be available on BBC Match of the Day at 10:45pm GMT on BBC One.
Spurs are currently four points behind Leicester in the League and will come into the fixture with the wind in their tails after the last minute equaliser by Kane. The north London club have lost only two games thus far in the league, against Manchester United on the opening day of the season and to a last minute winner by Newcastle United.
Mauricio Pochettino is likely to field a full team for the league fixture, having made a number of changes to the squad which started in the FA Cup. The return of the likes of Dele Alli in the starting XI will add some much needed flair to the Tottenham line-up, which barring a few glimpses of quality, were unable to trouble the Leicester defence for much of the game last weekend.
Meanwhile, Leicester know that a win here could take them top of the league yet again, with Arsenal taking on Liverpool at Anfield at the same time. Manager Claudio Ranieri has confirmed that striker Jamie Vardy may have a chance to feature in the starting XI, after missing the last game with an injury, for which he has to undergo surgery.
New signing Demarai Gray made the starting line-up against Spurs, but is likely to be kept on the bench this time around as he gets used to the rigours of the Premier League.
What managers say
Mauricio Pochettino: "It's true we are happy and very pleased to get the draw at the end. It's important for us to stay alive in the competition. But if we analyse, the first half, we deserved more. We dominated the whole game. But I'm happy. The performance was good. We have another chance. It is tough for us and tough for them [Leicester]. We need to be strong in our mind. We have a strong squad. Today showed that those not playing in the first team can fight for a place."
Claudio Ranieri: "Jamie is, more or less one month, one month and a half, is have a problem and he continued to play. Now without the problem he is much better. I'll see his fitness - if he starts from the beginning, if he comes with me on the bench, if he's ready to come with me on the bench. Every time he wants to play, I know him. This morning [Monday] he made warm-ups with the team, and they made a different job, and tomorrow I'll check. I think he could be available."
Betting odds ( 888Sport)
- Tottenham win: 14/19
- Draw: 21/10
- Leicester City win: 21/5
Team newshe north London club
Possible XI: Lloris; Walker, Alderweireld, Vertonghen, Rose; Dier, Dembele; Son, Alli, Eriksen, Kane.
Possible XI: Schmeichel; Simpson, Morgan, Huth, Fuchs; Mahrez, Inler, Kante, Albrighton; Okazaki, Vardy