Drew Barrymore and Will Kopelman
Drew Barrymore is expecting baby no. 2 With husband Will Kopelman.

Hollywood actress Drew Barrymore is expecting her second child with husband Will Kopelman.

A representative for the 50 First Dates star confirmed there was a bun in the oven to E! News, after rumours began circulating that she was pregnant.

Barrymore sent fans into a frenzy when she was pictured wearing a loose dress at the LACMA Art and Film Gala earlier in November. She is said to be in her second trimester.

The 38-year-old star and her art consultant hubby, who tied the knot in a Jewish ceremony on their southern Californian estate, are already the proud parents of daughter Olive, born in September 2012.

Barrymore has previously spoken about her desire to have more children soon after giving birth for the first time.

"I was an only child, and it was lonely," she told InStyle in the September issue.

"Some people love it and thrive on the independence, but I want my kids to have other kids around."

During an appearance on The Tonight Show in September, she told host Jay Leno that she wanted another child "right away".

"I grew up as an only child, and although that really works for some people and for some parents that's the way they want to do it."

"I want to be the Griswolds. I want the kids in the back rolling their eyes at Mom and Dad. I want Rusty and Audrey, theme parks and the whole nine."

Barrymore was previously married to British barman Jeremy Thomas and Canadian actor Tom Green.