Ellen DeGeneres Portia de Rossi
Ellen DeGeneres and Portia De Rossi are allegedly fighting following their South African vacation Frederic J Brown/AFP/Getty Images

American talk show host/comedian Ellen DeGeneres and her wife Portia De Rossi are again hit by reports that their marriage is in trouble.

According to InTouch Weekly, the 57-year-old Oscar host got into an argument with the 42-year-old Ally McBeal star about her recurring role on Scandal, following their South African vacation.

"Right after they got back, they had a huge fight about Portia's career," an alleged source said. "Portia told Ellen that once she starts filming Scandal again, she'll be married to her job."

"They wound up in a big screaming match and didn't speak again for days," the insider added. "It doesn't look like they will ever be able to get back on track. Ellen and Portia will soon be living separate lives."

DeGeneres married the Australian-American actress in 2008. However, there have been several reports since 2013 that the couple's marriage was on shaky grounds.

DeGeneres has done her best to quash the divorce rumours.

"The tabloids had a photo of Portia not wearing her wedding ring. She goes, 'I didn't wear it because when I ride horses and I'm holding the reins, it gives me a blister'!" DeGeneres told People last year in March.

"The truth is, and this is corny, I fall more in love with Portia all the time. I really do. She surprises me all the time," she said.

"It's what anyone experiences when you find that person that gets you, wants to take care of you, wants the best for you. We're really lucky because we know how rare it is," DeGeneres added.