David Silva-Samir Nasri
David Silva and Samir Nasri are set to miss Manchester City's clash against Tottenham due to injuriesGetty

Manchester City have suffered a blow as their star midfielder David Silva is set to miss the crucial clash against Tottenham Hotspur. Manuel Pellegrini will take his men to White Hart Lane as his side take on the north London club in the league clash on 26 September, Saturday.

The Spain international was withdrawn from the starting XI after he complained about his injury during the warm-up before City's 2-1 defeat to West Ham United at the Etihad. According to Goal.com, the 29-year-old will not feature for his side in the next league match against Tottenham.

Silva underwent scans after he was complaining about calf injuries over the past fortnight. He also missed City's 4-1 victory over Sunderland in the third round of the Capital One Cup. The midfielder has been urged to stay away from the pitch until he completely recovers from the muscle spasms.

The Premier League leaders will face German club Borussia Monchengladbach in the Champions League clash on 30 September, Wednesday. City are hopeful that Silva could be back in the starting lineup for the midweek fixture.

Silva has been playing in the number 10 role and in his absence, summer signing Kevin De Bruyne is likely to fill in for the Spaniard against Mauricio Pochettino's side. There is also concern over Samir Nasri's fitness for the Tottenham clash.

The former Arsenal midfielder picked up a knock and has missed City's last two fixtures against the Hammers and the Black Cats. He is unlikely to be fit for the upcoming fixture on Saturday. Pellegrini was also without the services of his skipper Vincent Kompany for the last two matches.

The City manager remains hopeful the Belgium defender could be fit to face Tottenham. When asked about Silva, Kompany and striker Wilfried Bony, Pellegrini said: "We'll see during the week the way they recover from now until Saturday. I hope we will recover a couple of them for the next game."

"I think it is also important for our team because we had eight players injured for this game (against Sunderland) that we cannot use: Silva, Nasri, Delph, Zabaleta, Kompany, Mangala, Bony and Kelechi."

"It is an important number of players that we couldn't use. That's why it was important to win the game and important to win in the way we played," he added.