Tom Thorpe
Thorpe is the highest profile of the latest departures from Old Trafford.Getty Images

Manchester United have confirmed the departure of four players after the annual Premier League released list was announced.

Ben Amos, Tom Thorpe, Callum Evans and Ryan McConnell are all looking for new clubs after United took the option not to renew their contracts into the 2015-16 season.

Amos made seven appearances for United across his seven-season career at Old Trafford while Thorpe's only professional outing came against West Ham United under Louis van Gaal.

Neither Evans nor McConnell made a single United appearance during their careers at the club having being mainstays of the youth sides.

The quartet represent the latest departures from United after they took the option not to make Radamel Falcao's loan move from Monaco permanent and allowed Tom Cleverley to join Everton after a season-long spell at Aston Villa.

Memphis Depay's arrival from PSV Eindhoven in May signalled the start of United's transfer business which is expected to continue upon the opening of the window on 1 July.

Exits from United could yet continue this summer, with David de Gea, Robin van Persie and Javier Hernandez all linked with moves away from the club.

De Gea is reportedly on the brink of joining Real Madrid after Iker Casillas decided against remaining at the Bernabeu after 16 years as a professional in the Spanish capital.

Completion of the deal is expected to see United enter the market for a replacement with Tottenham Hotspur's Hugo Lloris among the contenders.

Meanwhile, speculation over Van Persie's future continues to swell after the Netherlands international claimed there were negatives about life at United. The 31-year-old suffered from injury and a lack of form last term and has been linked with a move to Serie A.

Despite an uncertain loan spell with Real, Hernandez has demanded regular first team opportunities upon his return to United but with a new forward likely to be among Van Gaal's priorities this summer the Mexican's days appear numbered.