The Gunners last won the title in 2003-04 when they went the entire season unbeaten but recent years have seen the competition pass Wenger by.
Mourinho has used a flurry of combinations at the back, with the likes of Eric Bailly, Phil Jones, Chris Smalling and Victor Lindelof all getting into the team at some point.
Anthony Martial comes off the bench to score with nine minutes remaining as Manchester United beat Tottenham 1-0 at Old Trafford.
Rhian Brewster has scored hat-tricks against USA in the quarter-final and Brazil in the semi-final of the ongoing 2017 Fifa Under-17 World Cup in India.
Dele Alli has emerged as a key player under Mauricio Pochettino at Tottenham Hotspur. His form has seen him attract interest from top clubs across Europe.
Zlatan Ibrahimovic said he is close to returning from injury but is not ready to rush his return and risk a setback.
Zlatan Ibrahimovic suffered a knee injury in April and is still on the sidelines. Manchester United signed Romelu Lukaku in summer and the striker has impressed for the Red Devils.
Arsene Wenger has revealed that he is unlikely to make too many changes to his Premier League team and it will be almost the same as the one that beat Everton.
Kane experienced a number of largely unsuccessful loans in the lower reaches of English football before bursting onto the scene at Spurs.
Thomas Vermaelen, Arda Turan and Aleix Vidal, Rafinha and Ousmane Dembélé are also out, while Javier Mascherano is included despite suffering from illness.
The Swede suffered a serious knee ligament injury in April but could return to action as early as December.
Former Real Madrid goalkeeper Iker Casillas is not on the brink of leaving Porto amid renewed interest from Liverpool.
Manchester United were heavily linked with a move for Tottenham's Eric Dier in the summer but Jose Mourinho insists he got the player he always wanted in Nemanja Matic.
Antonio Conte has reiterated that the final decision on sales rests with Chelsea after being quizzed on the summer departure of Nathan Ake to Bournemouth.
Barcelona left-back Jordi Alba is expected to return to action for the Catalans's visit to Athletic Club Bilbao after having recovered from a thigh injury.
Unsworth watched over a much-improved performance as Everton lost to Chelsea on Wednesday (25 October) and has made no secret of his desire to take the reins at Goodison.
IBTimes UK looks at the Tottenham XI Mauricio Pochettino could pick to face Manchester United following the news that Harry Kane will miss out through injury.
Jurgen Klopp has defended Liverpool centre-back Dejan Lovren after the Croatian international's performance in the 4-1 defeat to Tottenham at Wembley.
Antonio Conte has confirmed that N'Golo Kante and Victor Moses will miss the trip to Bournemouth but the Chelsea midfielder could recover in time to face AS Roma.
Rhian Brewster's hat-tricks against USA and Brazil in the quarter-final and semi-final of the 2017 Fifa World Cup in India has helped England book a place in the final.
Everton signed Oneykuru from KAS Eupen in the summer transfer window before farming him straight out to Anderlecht on loan.
Phil Jones and Eric Bailly are in contention to return from injury when Manchester United host Tottenham Hotspur on Saturday.
Liverpool playmaker Philippe Coutinho is suffering with an adductor injury and is a doubt for Saturday's Premier League match against Huddersfield Town.
Barcelona have told Arda Turan, Aleix Vidal and Thomas Vermaelen that they can leave the club during the January transfer window.
Gueye joined Everton from Aston Villa for £7.1m in the summer of 2016 and has garnered many admirers in recent months.
Spurs have been in brilliant form this season and sit level on points with Jose Mourinho's men following their 4-1 thrashing of Liverpool last gameweek.
Pochettino accused United of "destabilising" Dier with a recent approach but holds no grudge against Mourinho, who he will come up against at Old Trafford on Saturday.
Ancelotti led Chelsea to a Premier League and FA Cup double in 2010 but was sacked the following year.
Silva is some bookmakers' third-favourite to replace Ronald Koeman at Everton bu insists he's happy at Watford.
Lamela has not played for Spurs for a year due to hip problems but Pochettino thinks the Argentine is "so close" to a return.