TNT Post will create more than 1,000 jobs when the private postal operator launches delivery services in Greater Manchester in November.
The subsidiary of PostNL will open 11 units in Manchester, Trafford, Salford, Wigan, and Bury, enabling the company to deliver to all households and businesses within the M postcode.
The employer has already seen 600 candidates apply for the new roles, which range from delivery men to back office support workers.
"The postal industry is undergoing great change and I am proud that TNT Post is able to create new jobs for people who need them and also to provide career opportunities for those who want to progress in a growing company," said Nick Wells, chief executive officer of TNT Post.
The new delivery service will operate alongside the traditional Royal Mail postman, but the TNT Post Postie will complete their deliveries using bicycles, according to the company.
Sir Richard Leese, leader of Manchester City Council, added: "This scale of investment and job creation in and around Manchester is always welcome and it's pleasing that TNT Post has decided to launch a major Greater Manchester operation."
The announcement comes as the government attempts to float TNT Post's state-owned competitor Royal Mail on the London Stock Market in October.
The sell-off, set to be one the biggest in British history, will see Royal Mail employees receive 10% of the organisation in shares, have priority over retail investors in purchasing stock, and have a smaller minimum purchase of £500, against £750 for the rest of the market.
The government has also said that 41% of the company will be on offer to investors, but city analysts doubt Royal Mail will meet the £3bn value needed to enter the FTSE100 on flotation.