Bunnie Xo's Alarming GLP-1 Side Effects: Suicidal Thoughts and More Revealed

GLP-1 recently became one of the most popular weight loss medications used by thousands of people not only in the US, but also in other parts of the world. It is mainly used to treat Type II diabetes by improving insulin secretion and to help manage weight by suppressing appetite and increasing the feeling of fullness. Even though the medication has helped hundreds of people diagnosed with Type II diabetes, it has also caused serious side effects in some of its users.

Today, various types of GLP-1 medications require a prescription from a physician. Some celebrities known to have tried either Mounjaro, Ozempic, or Wegovy include Oprah Winfrey, Whoopi Goldberg, Kelly Clarkson, Sharon Osbourne, Elon Musk, Bunnie Xo, Serena Williams, Meghan Trainor, and more. However, not everyone has shared the side effects that they have encountered.

GLP-1 Side Effects

During an interview with People, Bunnie Xo, whose real name is Alyssa DeFord, urged fans not to use GLP-1 medications without carefully considering the risks. The personality revealed that she developed suicidal ideations and started having visions after she started using the medication last year. Bunnie Xo also said that December 2025 was such a difficult and scary time for her because she started feeling depressed and wanted to die.

'You want to have anxiety because you want to be scared to die. You don't want to have depression because you literally don't care if you want to die. So yeah, it was really dark,' she said.

The podcast host also encouraged those who may be having similar thoughts about ending their life to seek help immediately and to remember that they are not alone.

'Please stay. Everybody, please stay because you're here for a reason and you're going through this, but do not make a permanent decision based on a temporary emotion because it will go away,' she said.

When asked why she decided to take a GLP-1 medication, Bunnie Xo explained that it was because her insulin levels were unstable, not because she wanted to lose weight. The podcast host's family also had a history of diabetes, particularly her parents.

Jelly Roll's Different Approach

Her husband, on the other hand, went viral after he lost almost 300 pounds without using Ozempic or similar medications. Jelly Roll revealed that he decided to have a healthier relationship with food, and he also started walking and exercising regularly to maintain his figure and improve his overall health.

On his wife's podcast, Jelly Roll said that he didn't want to take GLP-1 medication because, as a singer, it could destroy his vocal cords. During his interview with Men's Health magazine, it was revealed that the musician tried using weight loss drugs during the first two weeks of his journey, but he immediately stopped due to the extreme acid reflux that he experienced.

In 2020, Bunnie Xo's husband found himself at his highest weight at over 500 pounds. Following his wakeup call, Jelly Roll worked with a professional to address his food addiction similar to how he sought treatment for his drug addiction years earlier. His transformation has since inspired many of his fans to pursue healthier lifestyles through natural means.