Where to watch
Kick-off is at 7.45pm BST. Live TV coverage of the game will be available on Sky Sports 1 and 1 HD. Radio commentary will be available on BBC Radio 5 Live.
Liverpool welcome Tottenham to Anfield in what is one of three glamour fixtures in the fourth round of the League Cup – the other two being the Manchester derby and a London derby between West Ham United and Chelsea.
Liverpool and Tottenham have met once already this season in the Premier League and played out a draw at White Hart Lane. Wednesday's encounter (26 October) however is likely to see both managers' much changed lineups, which will not be their strongest. Jurgen Klopp and Mauricio Pochettino have both admitted that their squads will be a mixture of experience and youth consisting of players from the academy and the fringes of the first-team.
The Reds are unbeaten in nine games in all competitions and Klopp will be keen to continue the momentum. Last year's unbeaten finalists will face a difficult task as their opponents are also in good form, having lost just once in all competitions thus far.
Danny Ings will make his second appearance this season, as the manager looks to cautiously ease him into the first-team following a long-term injury, while Daniel Sturridge, who has struggled to break into the starting XI this season, is also likely to be given a chance to impress the manager.
Tottenham are without Harry Kane and Toby Alderweireld for the game against the Reds owing to injury, but the manager is likely to call up a number of academy players, who are on the fringes of the first-team. Cameron Carter-Vickers is likely to return at centre-back alongside Kevin Wimmer, while Tom Carroll and Harry Winks could start in midfield.
What managers say:
Jurgen Klopp [on Danny Ings]: It's really good. If I was being a little less sensitive I could say that is his job to do, but I am sensitive and I know it is not easy. He takes the situation in a perfect way but it's all for him. But it is all for him. He was a long time injured. He is fit now, everything is good and, with his attitude, all will be good in the end.
Mauricio Pochettino:"For me, it's Liverpool against Tottenham. Football is a collective sport. It's true that when you are involved in many competitions like we are, you can see that I rotate the squad in different games. Now it's to assess the team and take a different solution with freshness and compete in a different way. We have Liverpool and then key games like Leicester and Leverkusen. It's important to be clever."
Betting odds (betfair)
• Liverpool Win: 13/20
• Draw: 29/10
• Tottenham Win: 4
Possible XI: Mignolet; Clyne, Lovren, Klavan, Milner; Can, Lucas, Wijnaldum; Sturridge, Origi, Ings.
Possible XI: Vorm; Trippier, Wimmer, Carter-Vickers, Davies; Dier, Carroll; Lamela, Winks, Onomah; Janssen.