Arsenal manager Arsene Wenger is hopeful midfield pair Aaron Ramsey and Mesut Ozil will return in time for final two months of the season as the club chase a league and cup double.
Ramsey hasn't featured since the Boxing Day win over West Ham United and has suffered numerous setbacks in his return from a thigh injury.
Ozil went off at half time in midweek with a hamstring injury as Arsenal were knocked out of the Champions League by Bayern Munich in Germany.
While Ramsey is expected back in two weeks after close to three months out of action, Ozil may not return until mid-April with a grade-two hamstring strain.
"Ramsey takes longer than expected," said Wenger prior to the weekend meeting with Tottenham Hotspur. "He still has recurrent pains in his thigh. When will he be back? I believe it is 2 more weeks."
"[For Ozil] When the minimum is three, the maximum is six. Grade-two hamstring, let's say four weeks."
"Monreal is definitely available, Gibbs we are not sure."
Welshman Ramsey, 23, who scored eight goals in 18 games during the first half of the campaign, will definitely miss this weekend's trip to Spurs and the league games against Chelsea and Swansea City but could return for home match against Manchester City.
Ozil's prognosis is less positive and is expected to be unavailable until the FA Cup semi-final against Wigan Athletic on 12 April and for the final four games of the Premier League season.
In a week of on-field disappointment for Arsenal, reports have emerged that striker Nicklas Bendtner was involved in an incident with a Danish taxi driver in Copenhagen.
And while Wenger would not be drawn on the specifics of the incident, the Frenchman confirmed the club would reprimand the 26 year old for having returned to his homeland
"I don't know what happened," the Arsenal boss added. "The only thing that is for sure, nobody gave him any permission to go to Copenhagen. He will be fined for that."