US scientists have hailed a potential breakthrough in the coronavirus fight after a trial showed patients responding to an antiviral drug, fueling global hopes for a return to normal despite mounting deaths and abysmal economic figures.

A homeless man in Moscow gets a meal at s has a meal at the "Rescue Hangar" during the COVID-19 coronavirus lockdown Photo: AFP / Dimitar DILKOFF

The news was enough to propel a rebound on Wall Street even after data showed the pandemic had plunged the United States into its worst economic slump in a decade, and Germany predicted its biggest recession since the aftermath of World War II.

It came as the World Health Organization's emergency committee was due to meet Thursday for the first time in three months to discuss the evolution of the COVID-19 pandemic that has claimed more than 226,000 lives worldwide.

A clinical trial of the drug remdesivir showed that patients recovered about 30 percent faster than those on a placebo, in the first proof of successful treatment against the new disease.

COVID-19 testing station
A nurse awaits his next patient at a mobile COVID-19 testing station in a public school parking area in Compton, California Photo: AFP / Robyn Beck

"The data shows that remdesivir has a clear-cut, significant, positive effect in diminishing the time to recovery," Anthony Fauci, the top US epidemiologist who oversaw the study, told reporters.

Fauci likened the finding to the first retrovirals that worked, albeit with modest success, against HIV in the 1980s.

Lebanese Demonstrators
Lebanese demonstrators walk through the streets of the capital Beirut as anger over a spiralling economic crisis re-energised a months-old anti-government movement Photo: AFP / ANWAR AMRO

Remdesivir failed in trials against the Ebola virus and a smaller study, released last week by the WHO, found limited effects among patients in Wuhan, China, where the illness was first detected in December.

Novel Coronavirus
Health workers help a woman who tested positive for the novel coronavirus COVID-19, at Bagcilar in Istanbul Photo: AFP / Bulent Kilic

Senior WHO official Michael Ryan declined to weigh in on the latest findings, saying he had not reviewed the complete study.

"We are all hoping -- fervently hoping -- that one or more of the treatments currently under observation and under trial will result in altering clinical outcomes" and reducing deaths, he said.

Inmates from Villa Devoto prison
Inmates from Villa Devoto prison take part in a riot demanding measures to prevent the spread of the Covid-19 coronavirus, after a case was reported inside the detention center, in Buenos Aires Photo: AFP / JUAN MABROMATA

US President Donald Trump has accused the UN health agency of not responding quickly or aggressively enough, although critics say he is trying to deflect attention from his own response.

Guadalajara, Mexico
Workers build 700 graves at the Mezquitán Pantheon cemetery in preparation for possible victims of the novel COVID-19 coronavirus in Guadalajara, Mexico Photo: AFP / ULISES RUIZ

Itching to return to the campaign trail as he faces re-election, Trump announced he would resume travel next week with an event in the battleground state of Arizona -- but not yet resume rallies, as contagion remains a risk.

A man dressed as 'Yamraj'
A man dressed as 'Yamraj', the Hindu mythical angel of death, campaigns to raise awareness on the importance to stay home and maintain social distancing during an event organised by Delhi police Photo: AFP / SAJJAD HUSSAIN
125,000 cards sent to Captain Tom Moore
A selection of over 125,000 birthday cards sent to Captain Tom Moore, for his 100th birthday on April 30th, displayed in the Great Hall of Bedford School, in Bedford, north of London Photo: AFP / JUSTIN TALLIS

US virus fatalities soared past 60,000 on Wednesday. The country has suffered the most deaths, with Britain's toll shooting up to the world's third worst at over 26,000.

More than 27,000 people have died in Italy.

Novel Coronavirus
People wearing face masks visit a hair salon in Tokyo Photo: AFP / CHARLY TRIBALLEAU

Florida became the latest US state to move to reopen, with restaurants able to serve customers outdoors from Monday if tables are at least six feet (1.8 meters) apart.

Berlin Zoo
A man wearing a face mask and his child observe a California Sea Lion at Berlin's Zoo as it partially reopens for the public Photo: AFP / Tobias SCHWARZ

Experts have warned that only a vaccine will allow the full removal of restrictions that this year put half of humanity under some form of lockdown.

Governments are nevertheless increasingly loosening the more suffocating rules as their devastating impact on the global economy becomes clearer.

South Africa
Even during a strict lockdown, anti-poaching rangers in South Africa's Greater Kruger Park area continue on the front lines to guard one of the country’s most precious resources: its wildlife. Photo: AFPTV / Antoine DEMAISON

The US announced that economic output collapsed 4.8 percent in the first quarter -- ending more than a decade of expansion.

Federal Reserve chairman Jerome Powell warned that economic activity will likely drop "at an unprecedented rate" in the second quarter, in grim news for Trump.

Germany, Europe's largest economy, has succeeded in holding off the devastating death tolls seen elsewhere, but is still bracing for an overwhelming economic hit.

Germany "will experience the worst recession in the history of the federal republic" founded in 1949, Economy Minister Peter Altmaier warned, predicting that GDP would shrink by a record 6.3 percent.

The International Labour Organization said half the global workforce -- around 1.6 billion people -- are in "immediate danger of having their livelihoods destroyed."

One of the worst-hit sectors is the aviation industry.

World air traffic suffered a massive drop of more than half in March compared with the same period last year -- the "largest decline in recent history," the International Air Transport Association said.

US plane-builder Boeing announced plans to reduce its workforce by 10 percent and slash production while European giant Airbus also reported big losses.

An unprecedented drop in demand for fossil fuels means the pandemic is expected to cause global energy emissions to fall a record eight percent this year, the International Energy Agency said Thursday.

While the world keeps looking for signs of progress against the pandemic, research is also revealing frightening new details about COVID-19.

Britain and France have both warned of a possible coronavirus-related syndrome emerging in children -- including abdominal pain and inflammation around the heart.

"I am taking this very seriously. We have absolutely no medical explanation at this stage," French Health Minister Olivier Veran said.

Experts have also warned of longer-term psychological tolls on both children and adults after weeks or even months in isolation.

Unlike much of continental Europe, Britain has not unveiled a way to exit the lockdown.

The sharp rise in its COVID-19 toll, which caused Britain to surpass Spain, came as it included deaths in places such as care homes for the first time.

British Prime Minister Boris Johnson initially resisted shutting down the country -- and himself became the highest-profile coronavirus patient, fighting for his life in intensive care.

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