Peter Moores has been charged with resurrecting English cricket, having been reappointed as head coach five years after being sacked by the England and Wales Cricket Board.
Moores returns to the role to lead England in all forms of the game after beating Ashley Giles, Trevor Bayliss, Mick Newell and Mark Robinson to the role following a week-long interview process.
Sri Lanka coach Paul Farbrace will support the 51-year old, who led Lancashire to the Count Championship in 2011 but suffered an inauspicious spell as England coach between 2007 and 2009.
"I am very excited about the prospect of returning to a role I have done before and to building a strong relationship with Alastair Cook and the rest of the players and staff," Moores said. "In any time of change there comes opportunity and this is one I can't wait to get stuck into."
In 22 Tests, Moores won just eight as coach and his ill-fated two years in charge was ended after his capabilities were questioned by then captain Kevin Pietersen, who has been banished from the international scene since the 5-0 Ashes whitewash by Australia.
The appointment of Moores ends an overhaul of English cricket which includes the resignation of Flower as Test coach, the retention of captain Alastair Cook and promotion of Paul Downton to ECB managing director.
Downton said: "Peter has a great reputation around the world as an outstanding coach and he will return to the role as England head coach with a great deal more experience and understanding of the challenges that the role presents.
"There is no doubt that he is the leading English coach of his generation and I believe that this is his time.
"It was a really difficult decision to make as we had an outstanding field but the panel were unanimous in the choice of Peter and I know that support will be echoed around the counties."