Tottenham Hotspur have confirmed Danny Rose has undergone exploratory knee surgery, ending any hopes of him returning this season.
Rose, 26, was in superb form during the first half of the season, but an injury suffered in the goalless draw against Sunderland on 31 January brought his campaign to a shuddering halt.
Talk of a return to action emerged in April ahead of the club's FA Cup semi-final clash with Chelsea. When that fell by the wayside, the North London derby against Arsenal eight days later was suggested after he returned to group training, but that too was abandoned.
The England international was back in full training ahead of last Sunday's (14 May) meeting with Manchester United, Tottenham's last ever game at White Hart Lane, but was deemed "not match fit".
Tottenham have already secured runners-up spot in the Premier League ahead of their two final games of the season against Leicester City on Thursday and already-relegated Hull City on Sunday. Rose will have no role to play in either of those games, however.
"The club can confirm that Danny Rose has undergone exploratory surgery on his left knee today," a statement from the club read. "The England international sustained the injury in January against Sunderland. He recently returned to first-team training, however the problem has not been resolved fully therefore a decision has been made to proceed to surgery. He will return to action next season."
Rose will remain on the sidelines with Erik Lamela and Harry Winks, who have also been ruled out for the rest of the season as they continue their rehabilitations from respective hip and ankle injuries.
Spurs are also without the young trio of Kyle Walker-Peters, Josh Onomah and Cameron Carter-Vickers who have been called up for their respective national teams for the Under-20 World Cup in Brazil. Walker-Peters and Onomah have joined up with Paul Simpson's England side with Carter-Vickers named in the United States' 21-man squad.