A deadly winter weather system that brought record-busting cold to the southern and central United States, knocking out power for millions in oil-rich Texas, blanketed the East Coast in snow Thursday, disrupting coronavirus vaccinations.

The historic frigid blast has over the past week seen Arctic cold envelope much of the US sun belt unfamiliar with such extremes, leaving dozens of dead in its wake and several million Texans told to boil water before consuming it.

Waco Texas
A resident in Waco, Texas clears snow as the oil-rich state struggles to cope with a historic cold snap Photo: AFP / Matthew Busch

On Thursday, a "major" winter storm impacted an area stretching from Virginia up to the Northeast, bringing icy buildups and "treacherous" travel conditions, according to the National Weather Service.

Snow fell steadily across New York City throughout the day, forcing the cancelation of about 200 flights and delaying the opening of two Covid-19 vaccination sites after the storm disrupted dosage delivery.

By 4:50 pm (2150 GMT), meteorologists had recorded more than four inches (ten centimeters) of snow in lower Manhattan.

Texas snow storm
More than 500,000 Texas homes and businesses remained without electricity Thursday morning Photo: AFP / Matthew Busch

The Big Apple has already been blanketed by the white stuff twice this winter during two separate storms.

"The occasional snowstorm is always good but as we're getting closer to March it gets a little tiring. I'm ready for it to start being warm again," said 18-year-old student Kara Dickson.

A weather warning was in effect in New Jersey, where Governor Phil Murphy announced the temporary closure of several vaccination sites.

US snow storm
A blanket of snow covers the streets of Houston, Texas, a southern US state more accustomed to record-breaking heat than ice. An historic cold snap has been sweeping the country for several days as a result of an Arctic blast that is causing temperatures to plummet. Photo: AFPTV / Francois PICARD

"This may result in many appointments needing to be rescheduled," he said.

Across Texas, which has been hardest hit by the cold snap, utility companies were gradually restoring power though more than 350,000 homes and businesses remained without electricity late Thursday afternoon, according to PowerOutage.us.

US snow storm
A worker distributes salt in preparation for a snow storm at Wall Street in New York Photo: AFP / Angela Weiss

Texas power companies implemented rolling blackouts to avoid grids being overloaded as residents cranked up the heat. The surge in demand came as generating capacity dropped thanks to power stations and wind turbines freezing.

Texas snow storm
Keeping warm at the George R. Brown Convention Center in Houston, Texas Photo: AFP / Thomas Shea

David Hernandez, 38, spent the night at a Houston church with other people who had fled their homes.

"My car got stranded and I was trying to sleep in the car but it was just too cold. I had to come here," he said.

Texas authorities opened about 300 emergency "warming centers" across the state.

Lincoln Memorial
Men are seen outside of the Lincoln Memorial under a blanket of light snow in Washington, DC on February 18, 2021 Photo: AFP / MANDEL NGAN

Compounding the misery, thousands of Houston residents also suffered a loss of water pressure.

Nearly seven million Texans were advised to boil their water before drinking it or using for cooking, said Toby Baker, who heads the Texas Commission on Environmental Quality, adding that nearly 264,000 people were impacted by non-operational water systems.

Texas's woes have sparked outrage in the Lone Star State, the only one of the US's 48 continental states to have its own independent power grid.

Beto O'Rourke, a former Democratic presidential candidate from Texas, said it was at risk of becoming "a failed state."

Anger soared Thursday after it was revealed Texas Senator Ted Cruz had flown to the Mexican holiday resort of Cancun during the crisis.

As political rivals called for his resignation, Cruz justified the flight by saying his one-night stay was to drop his children off before he flew home.

Even though the Arctic air mass was beginning to loosen its grip in Texas and elsewhere in the south, the NWS said frigid temperatures would continue.

President Joe Biden ordered the Federal Emergency Management Agency to coordinate disaster relief efforts in Oklahoma and Louisiana after local officials declared emergencies.

Biden was forced to postpone until Friday a visit to the Pfizer Covid-19 vaccine manufacturing site in Kalamazoo, Michigan while federal government offices in Washington were closed Thursday.

Los Angeles' mayor announced that 12,500 people would have their vaccinations scheduled for Friday postponed due to dosage delays.

More than 30 storm-related deaths have been reported by US media since the cold weather arrived last week, many in traffic accidents.

Houston police said a woman and a girl died from carbon monoxide poisoning after sitting in a car in a garage with the engine running to keep warm.

Emergency medical authorities around Texas said dozens of others have been treated for suspected carbon monoxide poisoning.

The winter storm has spawned at least four tornadoes, according to Atlanta-based weather.com, including one in North Carolina on Monday that killed at least three people and injured 10.

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