Avon and Somerset Police investigating the disappearance of schoolgirl Becky Watts have arrested a 28-year-old man and a 21-year-old woman on suspicion of murder.
The pair were arrested on Saturday (28 February) on suspicion of kidnap and are in custody, where detectives have been granted a further 36 hours to question them.
The 16-year-old was last seen at her home in Crown Hill on 19 February and the police hunt for her has since intensified.
Becky left her home with her phone, laptop and tablet device but did not tell her friends or family where she was going.
A laptop that was discovered in woodland near her home has since been ruled out as belonging to the missing girl.
Police earlier called for anyone who had seen a black Vauxhall Zafira - registration HY06 HYA - between 19 and 23 February to come forward.
A police spokesperson said: "We are drawing upon all possible resources to help us. Additional officers from Wiltshire, Gloucestershire and Devon and Cornwall and police dogs from South Wales Police have been drafted in and support from the police helicopter.
"Search and missing persons' experts from the National Crime Agency, College of Policing and the National Missing Persons organisations continue to work with our enquiry team.
"We have extended our search parameters to include a house in Southmead and one in the Barton Hill area of Bristol. These are detailed, forensic searches which will take some time to complete.
"We continue to carry out both open land searches and detailed house to house enquiries in the local area.
"We have also conducted extensive CCTV enquiries and detailed analysis of traffic cameras in the area.
"I would appeal once again for anyone who may have any information on this case to come forward immediately. Someone out there might have vital information which could help us find Becky."