Liverpool forward Daniel Sturridge is a doubt for the Premier League trip to Swansea City after withdrawing from the England squad for the World Cup qualifier against Ukraine having failed to recover from a thigh problem.
The 24 year old missed the win over Moldova on Friday after picking up the injury in the warm-up prior to The Reds' 1-0 win over Manchester United, which saw Sturridge score the winning goal and play the full 90 minutes.
Sturridge's injury leaves England with just two fully-fit strikers for the crucial qualifier in Kiev against Ukraine on Tuesday, with Rickie Lambert expected to spearhead the attack ahead of Jermain Defoe.
"The FA can confirm that Daniel Sturridge will not return to the England squad ahead of the World Cup qualifier with Ukraine on Tuesday," an FA statement read.
"Club England medical staff have been in constant contact with their counterparts at Liverpool Football Club since he returned there on Thursday, his injury has not progressed as had been hoped and it is now clear that Sturridge will not be fit for the match in Kiev on Tuesday evening.
"No additions will be made to Roy Hodgson's squad of 23 players who travel to Ukraine on Sunday evening."
Ahead of the return of the Premier League this weekend, Sturridge has returned to Liverpool's Melwood training base for further treatment but having missed the successive internationals and not trained in between the former Chelsea and Manchester City man must be considered a doubt for the visit to Swansea.
Liverpool medical staff have a week to prepare Sturridge for the game in south Wales as the club looks to keep their 100% start to the season going.
Sturridge has scored in each of Liverpool's three 1-0 Premier League wins this season, against Stoke City, Aston Villa and United while he netted twice in the 4-2 League Cup victory over Notts County.
Should manager Brendan Rodgers be without Sturridge for his return to the Liberty Stadium, the Northern Irishman - who remains without Luis Suarez - could be forced to choose Iago Aspas to lead the attack.