Rafinha Alcantara is also back after missing the past two games due to a broken nose.
Mane, 24, joined the Reds from Southampton for £34m in June.
Lukaku has already scored 17 goals in all competitions this season for the Toffees.
Bournemouth are currently without a win in six games.
Burnley showed why they are so good at home by stifling Chelsea on Sunday.
Bale, 27, has been out of action since November due to an ankle injury.
Mata has flourished under Mourinho and is a regular member of the starting XI.
Mourinho described Chelsea as a "defensive team" over the weekend.
Ozil has assisted just two and scored none in his last eight Arsenal appearances.
Lingard has risen through the ranks to become a first-team regular.
Chelsea could further strengthen their grip on the Premier League title.
Toure has featured in every league game since making peace with Pep Guardiola in November.
Alli has blossomed into one of the stars of the Premier League at Spurs.
Dembele, 20, has scored 12 league goals for Celtic this season.
Arsenal bounced back from two league defeats with a 2-0 win over Hull City on 11 February.
Everton laboured to a 0-0 draw against struggling Middlesbrough.
Goals from Sadio Mane gave the Reds a much-needed win.
Boss insists he gave no indication about his future plans during his meeting with the former Arsenal striker.
Tottenham were woeful in the first half and barely improved in the second.
Wenger, 67, has been under pressure after Arsenal suffered back-to-back defeats against Watford and Chelsea.
Alexis Sanchez scored a controversial opener with his hand.
Arsene Wenger's current Arsenal contract will expire at the end of the season.
Burnley have collected 28 of their 29 points at home this season.
The France international scored one and created the other in the 2-0 win.
Vidal, 27, dislocated his right ankle in Barcelona's 6-0 win over Deportivo Alaves.
Jurgen Klopp's men are looking to get back to winning ways against Spurs.
United can move into fifth place with a win at Old Trafford.
Arsene Wenger's men got back to winning ways against the Tigers.
Dozens more were injured as hundreds of football supporters stormed the gates at the 4 de Janeiro Stadium.
The Arsenal manager finds his team 12 points behind leaders Chelsea.