Diego Costa will also miss the game due to suspension while Gary Cahill is still a doubt.
Pochettino could welcome back three players as Spurs' title challenge hangs in the balance.
Los Blancos host Eibar three days before Champions League quarter final second leg against Wolfsburg.
Once 24-year-old recovers from knee injury he will be ready to compete with Hector Bellerin at right-back.
The Italian "loves" the physical challenge of the Premier League and wants to stay at Old Trafford.
Arsene Wenger has revealed that Arsenal have a very scientific approach to games.
Payet and Kante are in the running for player of the season after impressive performances for West Ham and Leicester respectively.
Klopp's seven-year spell at Dortmund ended last season when he joined the Reds.
The 19-year-old attacking midfielder said he would be keen to stay at Betis one more season.
Disgraced former Fifa president to feature at University of Basel talk on Fifa reform.
Manager Ronald Koeman is hoping for a small turnover of players during the summer transfer window.
Wenger believes the team have found a good balance following their wins over Everton and Watford.
Divock Origi did not know he was starting until he got the team sheet.
AC Milan face Juventus in the Italian league clash on Saturday. Find out how to follow the match live in the UK.
Gabriel has started in the last eight games for Arsenal.
Liverpool beat competition from Manchester City to sign Daniel Trickett-Smith from Crewe Alexandra in 2012.
Jose Mourinho has not been in management since being sacked from Chelsea.
Alvaro Morata is likely to head back to Real Madrid before making the move to Arsenal.
Young and Jones made successful injury comebacks with the United U21 side on Monday against Chelsea.
Jurgen Klopp says the blow is "really bad news" for the Reds after losing their skipper.
Boga is 'in the same boat' as Rennes prodigy Ousmane Dembele, according to manager Rolland Courbis.
Xhaka has previously admitted a move to the Premier League would be a childhood dream of his.
Real Madrid host Eibar on Saturday three days before second-leg against Wolfsburg.
Turkish international joined Barcelona from Atletico Madrid in a deal worth £27.5m last summer.
Live coverage as Jurgen Klopp returns to Dortmund for the first time as an opposition coach.
Guidolin suggested earlier this week that he would be happy to replace Chelsea-bound Conte as Italy manager.
Former Hammer Dean Ashton says Ibrahimovic is worthy of his £600,000-a-week wage demands.
Zlatan Ibrahimovic is keen to continue playing at the highest level if he leaves PSG this summer.
British pair lead hunt for gold this summer according to former Olympic champion.
Gunners boss also claims he watched Dimitri Payet "many times" before his summer switch to West Ham.