Chancellor George Osborne attempted to build on Greater Manchester's ambitious devolution deal signed in November 2014, announcing the region will keep its extra business rates revenue.
Osborne said the government will pilot a new scheme in Greater Manchester and Cheshire East to enable the retention of 100% of any additional business rate growth, starting in April.
This "will mean local areas will see the full benefits of policy decisions that increase the local growth rate and business rate revenues, sharpening incentives to boost jobs and growth".
A similar a pilot scheme will also be rolled out in Cambridgeshire and Peterborough, starting in April.
West Yorkshire will also be given new powers over skills, business support and transport, the chancellor's budget has outlined.
Lord Livingston, the Minister for Trade and Investment, said in a statement: "Ensuring our Northern cities can attract the investment they need is vital to building our vision of a Northern Powerhouse that is greater than the sum of its parts and can compete on the global stage alongside London.
"This new money will allow UKTI to help more businesses in our northern cities to achieve success overseas and also secure the investment needed for 21st-century transport connectivity which is at last becoming a reality," he said.