Three bomb blasts have struck a mosque in northern Nigeria's largest city, Kano, during Friday prayers, according to local reports.
"These people have bombed the mosque. I am face to face with people screaming," Reuters quoted Chijjani Usman, a local reporter.
The number of casualties has not yet been confirmed but it is feared that many have been killed and injured by the explosion.
No group has yet claimed responsibility but suspicion is likely to fall on the Islamist militant group Boko Haram.
The Emir of Kano, Sanusi Lamido, regularly prays at the Central Mosque in Kano but is currently in Saudi Arabia, according to local media.
The mosque which was targeted by the group is situated next to the Emir's palace in the city. The proximity of the attack to Lamido's palace may provide a motivation for the attack as he serves as an authority figure against radical Islamism.
Earlier this month, Lamido gave his support to vigilantes fighting against the terror group and called on more people to defend against their attacks, saying they should "acquire what they need" to protect themselves.
A staff member at the palace and eyewitness told Reuters: "After multiple explosions, they also opened fire. I cannot tell you the level of casualties because we all ran away."
The terror group have carried out a wave of attacks in northern Nigeria in their quest to establish an Islamic caliphate in similar fashion to that of the Islamic State [IS] in Iraq and Syria.
Boko Haram have conducted a number of attacks on their fellow Muslims in the country's north, for example a massacre at a mosque in Maiduguri last year, contradicting assumptions that the group only target Christians or "non-believers".
It is believed that the group target fellow Muslims because they do not wish to follow their extremist cause of creating a caliphate in northern Nigeria.
The group also believes that it will replace regional religious leaders - who they see as corrupt and too close to Goodluck Jonathan's secular administration - if they are able to kill them.
According to Human Rights Watch, the militants have killed at least 2,053 people since the beginning of 2014, but researchers at the John Hopkins University School of International Studies estimate that 7,000 people have been killed in the 12 months between July 2013 and June this year.