Where to watch live
Kick-off is at 8pm BST. Live coverage of the match is available on Sky Sports 1 and Sky Sports 1 HD. Radio commentary of the game will be available on BBC Radio 5 Live.
Chelsea appointed Antonio Conte as their manager earlier this year, replacing interim manager Guus Hiddink at the west London club. Conte joined the Blues after he stepped down from his post as Italy manager following their exit from the European championship in France.
The former Juventus manager has helped the Stamford Bridge outfit complete the signings of Michy Batshuayi and Premier League winning midfielder N'Golo Kante. The latter arrived at Chelsea from English champions Leicester City.
Kante is likely to be Conte's key player in the centre of the pitch and the Italian coach will be hoping he can emulate his Leicester City form at Chelsea. It will be Conte's first match at the Bridge since his appointment as the London club's new manager.
Conte will be hoping to start the season on a brighter note by sealing three points over their local rivals. However, he will be aware that there will be tough competition from the Hammers on Monday.
West Ham, on the other hand have not enjoyed good results in the pre-season as they have managed to win only two out of all the eight fixtures. Slaven Bilic saw his side beat Arsenal at the Emirates and he will be hoping the Hammers can seal another win on opening day when they face Chelsea.
What managers say
Antonio Conte: "I am not very relaxed.This is a fantastic experience for me – the first time I have managed a new team in a new league and in a new country. It is a fantastic challenge and, for this reason, I am not much relaxed. We are working very hard to be prepared and we have to do a lot of work to improve."
Slaven Bilic: "It is the best league to work in, to play in, the most competitive one and the most covered one in the whole world. This is the NBA, this is Hollywood. And we are human, so we want to be a part of something big."
Betting Odds (betfair)
- Chelsea: 13/20
- Draw: 3
- West Ham United: 9/2
- Last five (all competitions): W W L W W
- Last result: Werder Bremen 2-4 Chelsea
West Ham United
- Last five (all competitions): L W L W L
- Last result: West Ham United 2-3 Juventus
- Injured: Kurt Zouma
- Doubtful: John Terry
- Suspended: N/A
Possible XI: Courtois; Ivanovic, Terry, Cahill, Azpilicueta; Kante; Willian, Oscar, Matic, Hazard; Costa.
West Ham United
- Injured: Aaron Cresswell, Manuel Lanzini, Doneil Henry, Diafra Sakho
- Doubtful: Gokhan Tore
- Suspended: Chris Smalling, Paul Pogba
Possible XI: Adrian; Antonio, Reid, Ogbonna, Masuaku; Kouyate, Nordtveit, Noble; Feghouli, Carroll, Ayew.