Liverpool have suffered a major blow as manager Brendan Rodgers confirmed that Daniel Sturridge has suffered a calf injury during training.
The England international was just making his comeback from a thigh strain that has kept him out for the last one month and the current injury suffered during a training session at Melwood could see him sidelined for up to a month.
The striker was pencilled in to return to first-team action on Sunday against Queens Park Rangers, but the latest injury setback will see him miss crucial clashes, including the double header against Real Madrid in the Champions League.
"Daniel has pulled his calf. He's looking at being out for another two to four weeks," Rodgers told the Liverpool Echo on Friday.
"It's a big blow as we were looking forward to welcoming Daniel back. He has worked tirelessly," the Reds boss added.
"But we have other players training hard and working hard and we will turn to them. It's why we bulked up the squad in the summer."
However, on the upside, the Reds have plenty of other key players, who have returned to training and could be available for the crucial run of fixtures in the next three weeks.
"Thankfully, we have got a number of our other injured players back. Joe Allen is training and looking really well, Emre Can is back, Glen Johnson is back in. So that side is looking healthy."
Rodgers is also happy to welcome back defender Dejan Lovren who has recovered from the injury he sustained on international duty and is set to be available for the weekend clash against QPR.
"Dejan will hopefully be fine for the weekend," the Northern Irishman added.